First Report of Klebsiella pneumoniae-Carbapenemase-3-Producing Escherichia coli ST479 in Poland
Joint Authors
Sacha, Paweł
Olszańska, Dorota
Majewski, Piotr
Sieńko, Anna
Jurczak, Anna
Tryniszewska, Elżbieta
Wieczorek, Piotr
Jaworowska, Jadwiga
Ojdana, Dominika
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
An increase in the antibiotic resistance among members of the Enterobacteriaceae family has been observed worldwide.
Multidrug-resistant Gram-negative rods are increasingly reported.
The treatment of infections caused by Escherichia coli and other Enterobacteriaceae has become an important clinical problem associated with reduced therapeutic possibilities.
Antimicrobial carbapenems are considered the last line of defense against multidrug-resistant Gram-negative bacteria.
Unfortunately, an increase of carbapenem resistance due to the production of Klebsiella pneumoniae carbapenemase (KPC) enzymes has been observed.
In this study we describe the ability of E.
coli to produce carbapenemase enzymes based on the results of the combination disc assay with boronic acid performed according to guidelines established by the European Community on Antimicrobial Susceptibility Testing (EUCAST) and the biochemical Carba NP test.
Moreover, we evaluated the presence of genes responsible for the production of carbapenemases (blaKPC, blaVIM, blaIMP, blaOXA-48) and genes encoding other β-lactamases (blaSHV, blaTEM, blaCTX-M) among E.
coli isolate.
The tested isolate of E.
coli that possessed the blaKPC-3 and blaTEM-34 genes was identified.
The tested strain exhibited susceptibility to colistin (0.38 μg/mL) and tigecycline (1 μg/mL).
This is the first detection of blaKPC-3 in an E.
coli ST479 in Poland.
American Psychological Association (APA)
Ojdana, Dominika& Sacha, Paweł& Olszańska, Dorota& Majewski, Piotr& Wieczorek, Piotr& Jaworowska, Jadwiga…[et al.]. 2015. First Report of Klebsiella pneumoniae-Carbapenemase-3-Producing Escherichia coli ST479 in Poland. BioMed Research International،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1054768
Modern Language Association (MLA)
Ojdana, Dominika…[et al.]. First Report of Klebsiella pneumoniae-Carbapenemase-3-Producing Escherichia coli ST479 in Poland. BioMed Research International No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1054768
American Medical Association (AMA)
Ojdana, Dominika& Sacha, Paweł& Olszańska, Dorota& Majewski, Piotr& Wieczorek, Piotr& Jaworowska, Jadwiga…[et al.]. First Report of Klebsiella pneumoniae-Carbapenemase-3-Producing Escherichia coli ST479 in Poland. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1054768
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054768