Evaluation of Antibacterial Activity of Some Traditionally Used Medicinal Plants against Human Pathogenic Bacteria
Joint Authors
Marasini, Bishnu P.
Baral, Pankaj
Aryal, Pratibha
Ghimire, Kashi R.
Neupane, Sanjiv
Dahal, Nabaraj
Singh, Anjana
Ghimire, Laxman
Shrestha, Kanti
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The worldwide increase of multidrug resistance in both community- and health-care associated bacterial infections has impaired the current antimicrobial therapy, warranting the search for other alternatives.
We aimed to find the in vitro antibacterial activity of ethanolic extracts of 16 different traditionally used medicinal plants of Nepal against 13 clinical and 2 reference bacterial species using microbroth dilution method.
The evaluated plants species were found to exert a range of in vitro growth inhibitory action against the tested bacterial species, and Cynodon dactylon was found to exhibit moderate inhibitory action against 13 bacterial species including methicillin-resistant Staphylococcus aureus, imipenem-resistant Pseudomonas aeruginosa, multidrug-resistant Salmonella typhi, and S.
typhimurium.
The minimum inhibitory concentration (MIC) values of tested ethanolic extracts were found from 31 to >25,000 μg/mL.
Notably, ethanolic extracts of Cinnamomum camphora, Curculigo orchioides, and Curcuma longa exhibited the highest antibacterial activity against S.
pyogenes with a MIC of 49, 49, and 195 μg/mL, respectively; whereas chloroform fraction of Cynodon dactylon exhibited best antibacterial activity against S.
aureus with a MIC of 31 μg/mL.
Among all, C.
dactylon, C.
camphora, C.
orchioides, and C.
longa plant extracts displayed a potential antibacterial activity of MIC < 100 μg/mL.
American Psychological Association (APA)
Marasini, Bishnu P.& Baral, Pankaj& Aryal, Pratibha& Ghimire, Kashi R.& Neupane, Sanjiv& Dahal, Nabaraj…[et al.]. 2015. Evaluation of Antibacterial Activity of Some Traditionally Used Medicinal Plants against Human Pathogenic Bacteria. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054817
Modern Language Association (MLA)
Marasini, Bishnu P.…[et al.]. Evaluation of Antibacterial Activity of Some Traditionally Used Medicinal Plants against Human Pathogenic Bacteria. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054817
American Medical Association (AMA)
Marasini, Bishnu P.& Baral, Pankaj& Aryal, Pratibha& Ghimire, Kashi R.& Neupane, Sanjiv& Dahal, Nabaraj…[et al.]. Evaluation of Antibacterial Activity of Some Traditionally Used Medicinal Plants against Human Pathogenic Bacteria. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054817
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054817