Ganglion Cell Complex Evaluation in Exudative Age-Related Macular Degeneration after Repeated Intravitreal Injections of Ranibizumab
Joint Authors
Perdicchi, Andrea
Peluso, Giacomo
Iacovello, Daniela
Balestrieri, Marco
Delle Fave, Martina
Abdolrahimzadeh, Solmaz
Scuderi, Gian Luca
Fenicia, Vito
Recupero, Santi Maria
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To detect the effects of intravitreal ranibizumab injections on GCC in patients with wet AMD.
Methods.
32 wet AMD eyes were selected and submitted at three ranibizumab injections.
RTVue-OCT GCC and MM5 protocol were performed before treatment and twenty days after each injection.
Results.
At baseline mean GCC thickness was 93.9 ± 18.5 μm.
Twenty days after each intravitreal injection it was, respectively, 85.8 ± 10.1, 86.5 ± 9.3, and 91.1 ± 11.5 μm, without statistical significance.
A significant improvement in visual acuity (P = 0.031) and a reduction of mean foveal (P = 0.001) and macular thickness (P = 0.001) were observed.
Conclusion.
The clinical results confirm therapeutic efficacy of intravitreal injections of ranibizumab in wet AMD.
A contemporary not statistically significant reduction of GCC thickness suggests that the loading phase of ranibizumab does not have any toxic effects on ganglion cell complex.
American Psychological Association (APA)
Perdicchi, Andrea& Peluso, Giacomo& Iacovello, Daniela& Balestrieri, Marco& Delle Fave, Martina& Abdolrahimzadeh, Solmaz…[et al.]. 2015. Ganglion Cell Complex Evaluation in Exudative Age-Related Macular Degeneration after Repeated Intravitreal Injections of Ranibizumab. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054822
Modern Language Association (MLA)
Perdicchi, Andrea…[et al.]. Ganglion Cell Complex Evaluation in Exudative Age-Related Macular Degeneration after Repeated Intravitreal Injections of Ranibizumab. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054822
American Medical Association (AMA)
Perdicchi, Andrea& Peluso, Giacomo& Iacovello, Daniela& Balestrieri, Marco& Delle Fave, Martina& Abdolrahimzadeh, Solmaz…[et al.]. Ganglion Cell Complex Evaluation in Exudative Age-Related Macular Degeneration after Repeated Intravitreal Injections of Ranibizumab. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054822
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054822