Genepleio Software for Effective Estimation of Gene Pleiotropy from Protein Sequences
Joint Authors
Chen, Wenhai
Chen, Dandan
Zhao, Ming
Zou, Yangyun
Zeng, Yanwu
Gu, Xun
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Though pleiotropy, which refers to the phenomenon of a gene affecting multiple traits, has long played a central role in genetics, development, and evolution, estimation of the number of pleiotropy components remains a hard mission to accomplish.
In this paper, we report a newly developed software package, Genepleio, to estimate the effective gene pleiotropy from phylogenetic analysis of protein sequences.
Since this estimate can be interpreted as the minimum pleiotropy of a gene, it is used to play a role of reference for many empirical pleiotropy measures.
This work would facilitate our understanding of how gene pleiotropy affects the pattern of genotype-phenotype map and the consequence of organismal evolution.
American Psychological Association (APA)
Chen, Wenhai& Chen, Dandan& Zhao, Ming& Zou, Yangyun& Zeng, Yanwu& Gu, Xun. 2015. Genepleio Software for Effective Estimation of Gene Pleiotropy from Protein Sequences. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054823
Modern Language Association (MLA)
Chen, Wenhai…[et al.]. Genepleio Software for Effective Estimation of Gene Pleiotropy from Protein Sequences. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054823
American Medical Association (AMA)
Chen, Wenhai& Chen, Dandan& Zhao, Ming& Zou, Yangyun& Zeng, Yanwu& Gu, Xun. Genepleio Software for Effective Estimation of Gene Pleiotropy from Protein Sequences. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054823
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054823