Obesity and Cancer Progression: Is There a Role of Fatty Acid Metabolism?
Joint Authors
Balaban, Seher
Lee, Lisa S.
Schreuder, Mark
Hoy, Andrew J.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-19
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Currently, there is renewed interest in elucidating the metabolic characteristics of cancer and how these characteristics may be exploited as therapeutic targets.
Much attention has centered on glucose, glutamine and de novo lipogenesis, yet the metabolism of fatty acids that arise from extracellular, as well as intracellular, stores as triacylglycerol has received much less attention.
This review focuses on the key pathways of fatty acid metabolism, including uptake, esterification, lipolysis, and mitochondrial oxidation, and how the regulators of these pathways are altered in cancer.
Additionally, we discuss the potential link that fatty acid metabolism may serve between obesity and changes in cancer progression.
American Psychological Association (APA)
Balaban, Seher& Lee, Lisa S.& Schreuder, Mark& Hoy, Andrew J.. 2015. Obesity and Cancer Progression: Is There a Role of Fatty Acid Metabolism?. BioMed Research International،Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1054839
Modern Language Association (MLA)
Balaban, Seher…[et al.]. Obesity and Cancer Progression: Is There a Role of Fatty Acid Metabolism?. BioMed Research International No. 2015 (2015), pp.1-17.
https://search.emarefa.net/detail/BIM-1054839
American Medical Association (AMA)
Balaban, Seher& Lee, Lisa S.& Schreuder, Mark& Hoy, Andrew J.. Obesity and Cancer Progression: Is There a Role of Fatty Acid Metabolism?. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1054839
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054839