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Potential Role of MicroRNA-210 as Biomarker in Human Cancers Detection: A Meta-Analysis
Joint Authors
Lu, Jiongjiong
Xie, Feng
Geng, Li
Shen, Weifeng
Sui, Chengjun
Yang, Jiamei
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
We conducted this meta-analysis aimed to evaluate diagnostic accuracy of miR-210 in human cancers.
A total of 673 cancer patients and 606 cancer-free individuals from 13 studies were contained in this meta-analysis.
The overall diagnostic results in our study showed that the pooled sensitivity was 0.70, specificity was 0.76, and the AUC was 0.80.
In addition, the PLR and NLR were 2.9 and 0.39, with DOR of 8.
After the outliner exclusion detected by sensitivity analysis, these parameters had minimal change, which confirmed the stability of our work.
The results in our studies showed that the miR-210 assay yielded relatively moderate accuracy in cancer patients and cancer-free individual differentiation.
More basic researches are needed to highlight its role as supplement in clinical treatment.
American Psychological Association (APA)
Lu, Jiongjiong& Xie, Feng& Geng, Li& Shen, Weifeng& Sui, Chengjun& Yang, Jiamei. 2015. Potential Role of MicroRNA-210 as Biomarker in Human Cancers Detection: A Meta-Analysis. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054968
Modern Language Association (MLA)
Lu, Jiongjiong…[et al.]. Potential Role of MicroRNA-210 as Biomarker in Human Cancers Detection: A Meta-Analysis. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1054968
American Medical Association (AMA)
Lu, Jiongjiong& Xie, Feng& Geng, Li& Shen, Weifeng& Sui, Chengjun& Yang, Jiamei. Potential Role of MicroRNA-210 as Biomarker in Human Cancers Detection: A Meta-Analysis. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1054968
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054968