Ocular Blood Flow and Normal Tension Glaucoma

Joint Authors

Fan, Ning
Wang, Pei
Tang, Li
Liu, Xuyang

Source

BioMed Research International

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-10-19

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Medicine

Abstract EN

Normal tension glaucoma (NTG) is known as a multifactorial optic neuropathy characterized by progressive retinal ganglion cell death and glaucomatous visual field loss, even though the intraocular pressure (IOP) does not exceed the normal range.

The pathophysiology of NTG remains largely undetermined.

It is hypothesized that the abnormal ocular blood flow is involved in the pathogenesis of this disease.

A number of evidences suggested that the vascular factors played a significant role in the development of NTG.

In recent years, the new imaging techniques, fluorescein angiography, color Doppler imaging (CDI), magnetic resonance imaging (MRI), and laser speckle flowgraphy (LSFG), have been used to evaluate the ocular blood flow and blood vessels, and the impaired vascular autoregulation was found in patients with NTG.

Previous studies showed that NTG was associated with a variety of systemic diseases, including migraine, Alzheimer’s disease, primary vascular dysregulation, and Flammer syndrome.

The vascular factors were involved in these diseases.

The mechanisms underlying the abnormal ocular blood flow in NTG are still not clear, but the risk factors for glaucomatous optic neuropathy likely included oxidative stress, vasospasm, and endothelial dysfunction.

American Psychological Association (APA)

Fan, Ning& Wang, Pei& Tang, Li& Liu, Xuyang. 2015. Ocular Blood Flow and Normal Tension Glaucoma. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054991

Modern Language Association (MLA)

Fan, Ning…[et al.]. Ocular Blood Flow and Normal Tension Glaucoma. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1054991

American Medical Association (AMA)

Fan, Ning& Wang, Pei& Tang, Li& Liu, Xuyang. Ocular Blood Flow and Normal Tension Glaucoma. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054991

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1054991