Blood Brain Barrier: A Challenge for Effectual Therapy of Brain Tumors
Joint Authors
Bhowmik, Arijit
Khan, Rajni
Ghosh, Mrinal Kanti
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-19
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
Brain tumors are one of the most formidable diseases of mankind.
They have only a fair to poor prognosis and high relapse rate.
One of the major causes of extreme difficulty in brain tumor treatment is the presence of blood brain barrier (BBB).
BBB comprises different molecular components and transport systems, which in turn create efflux machinery or hindrance for the entry of several drugs in brain.
Thus, along with the conventional techniques, successful modification of drug delivery and novel therapeutic strategies are needed to overcome this obstacle for treatment of brain tumors.
In this review, we have elucidated some critical insights into the composition and function of BBB and along with it we have discussed the effective methods for delivery of drugs to the brain and therapeutic strategies overcoming the barrier.
American Psychological Association (APA)
Bhowmik, Arijit& Khan, Rajni& Ghosh, Mrinal Kanti. 2015. Blood Brain Barrier: A Challenge for Effectual Therapy of Brain Tumors. BioMed Research International،Vol. 2015, no. 2015, pp.1-20.
https://search.emarefa.net/detail/BIM-1055059
Modern Language Association (MLA)
Bhowmik, Arijit…[et al.]. Blood Brain Barrier: A Challenge for Effectual Therapy of Brain Tumors. BioMed Research International No. 2015 (2015), pp.1-20.
https://search.emarefa.net/detail/BIM-1055059
American Medical Association (AMA)
Bhowmik, Arijit& Khan, Rajni& Ghosh, Mrinal Kanti. Blood Brain Barrier: A Challenge for Effectual Therapy of Brain Tumors. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-20.
https://search.emarefa.net/detail/BIM-1055059
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055059