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Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify?
Author
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Type 1 diabetes (T1D) is one of the most common chronic diseases with childhood onset, and the disease has increased two- to fivefold over the past half century by as yet unknown means.
T1D occurs when the body’s immune system turns against itself so that, in a very specific and targeted way, it destroys the pancreatic β-cells.
T1D results from poorly defined interactions between susceptibility genes and environmental determinants.
In contrast to the rapid progress in finding T1D genes, identification and confirmation of environmental determinants remain a formidable challenge.
This review article will focus on factors which have to be evaluated and decision to take before starting a new prospective cohort study.
Considering all the large ongoing prospective studies, new and more conclusive data than that obtained so far should instead come from international collaboration on the ongoing cohort studies.
American Psychological Association (APA)
Rønningen, Kjersti S.. 2015. Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify?. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055062
Modern Language Association (MLA)
Rønningen, Kjersti S.. Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify?. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1055062
American Medical Association (AMA)
Rønningen, Kjersti S.. Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify?. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055062