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In Vivo Osseointegration Performance of Titanium Dioxide Coating Modified Polyetheretherketone Using Arc Ion Plating for Spinal Implant Application
Joint Authors
He, Ju-Liang
Tsou, Hsi-Kai
Chi, Meng-Hui
Hung, Yi-Wen
Chung, Chi-Jen
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-04
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Polyetheretherketone (PEEK), which has biomechanical performance similar to that of human cancellous bone, is used widely as a spinal implant material.
However, its bioinertness and hydrophobic surface properties result in poor osseointegration.
This study applies a novel modification method, arc ion plating (AIP), that produces a highly osteoblast compatible titanium dioxide (TiO2) coatings on a PEEK substrate.
This PEEK with TiO2 coating (TiO2/PEEK) was implanted into the femurs of New Zealand white male rabbits to evaluate its in vivo performance by the push-out test and histological observation.
Analytical results show that AIP can prepare TiO2 coatings on bullet-shaped PEEK substrates as implant materials.
After prolonged implantation in rabbits, no signs of inflammation existed.
Newly regenerated bone formed more prominently with the TiO2/PEEK implant by histological observation.
The shear strength of the bone/implant interface increases as implantation period increases.
Most importantly, bone bonding performance of the TiO2/PEEK implant was superior to that of bare PEEK.
The rutile-TiO2 coatings achieved better osseointegration than the anatase-TiO2 coatings.
Therefore, AIP-TiO2 can serve as a novel surface modification method on PEEK for spinal interbody fusion cages.
American Psychological Association (APA)
Tsou, Hsi-Kai& Chi, Meng-Hui& Hung, Yi-Wen& Chung, Chi-Jen& He, Ju-Liang. 2015. In Vivo Osseointegration Performance of Titanium Dioxide Coating Modified Polyetheretherketone Using Arc Ion Plating for Spinal Implant Application. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055100
Modern Language Association (MLA)
Tsou, Hsi-Kai…[et al.]. In Vivo Osseointegration Performance of Titanium Dioxide Coating Modified Polyetheretherketone Using Arc Ion Plating for Spinal Implant Application. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1055100
American Medical Association (AMA)
Tsou, Hsi-Kai& Chi, Meng-Hui& Hung, Yi-Wen& Chung, Chi-Jen& He, Ju-Liang. In Vivo Osseointegration Performance of Titanium Dioxide Coating Modified Polyetheretherketone Using Arc Ion Plating for Spinal Implant Application. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055100
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055100