Is Infusion of Subhypnotic Propofol as Effective as Dexamethasone in Prevention of Postoperative Nausea and Vomiting Related to Laparoscopic Cholecystectomy? A Randomized Controlled Trial
Joint Authors
Aksoy, Mehmet
Dostbil, Aysenur
Celik, Mine Gursac
Ince, Ilker
Ahiskalioglu, Ali
Comez, Mehmet
Erdem, Ali Fuat
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Postoperative nausea and vomiting (PONV) is one of common complications in patients undergoing laparoscopic cholecystectomy (LC).
Aim of this study was to compare the efficacy of subhypnotic (1 mg/kg/h) infusion of propofol with dexamethasone on PONV in patients undergoing LC.
Methods.
A total of 120 patients were included in this randomized, double-blind, placebo-controlled study.
Patients were randomly assigned to 3 groups; patients of group dexamethasone (group D) were administrated 8 mg dexamethasone before induction of anesthesia, patients of group propofol (group P) were infused to subhypnotic (1 mg/kg/h) propofol during operation and patients of group control (group C) were applied infusion of 10% intralipid.
The incidence of PONV and needs for rescue analgesic and antiemetic were recorded in the first 24 h postoperatively.
Results.
In the 0–24 h, the incidence of PONV was significantly lower in the group D and group P compared with the group C (37.5%, 40%, and 72.5%, resp.).
There was no significant difference in the incidence of PONV and use of antiemetics and analgesic between group D and group P.
Conclusion.
We concluded that infusion of propofol 1 mg/kg/h is as effective as dexamethasone for the prevention of PONV during the first 24 hours after anesthesia in patients undergoing LC.
American Psychological Association (APA)
Celik, Mine Gursac& Dostbil, Aysenur& Aksoy, Mehmet& Ince, Ilker& Ahiskalioglu, Ali& Comez, Mehmet…[et al.]. 2015. Is Infusion of Subhypnotic Propofol as Effective as Dexamethasone in Prevention of Postoperative Nausea and Vomiting Related to Laparoscopic Cholecystectomy? A Randomized Controlled Trial. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1055146
Modern Language Association (MLA)
Celik, Mine Gursac…[et al.]. Is Infusion of Subhypnotic Propofol as Effective as Dexamethasone in Prevention of Postoperative Nausea and Vomiting Related to Laparoscopic Cholecystectomy? A Randomized Controlled Trial. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1055146
American Medical Association (AMA)
Celik, Mine Gursac& Dostbil, Aysenur& Aksoy, Mehmet& Ince, Ilker& Ahiskalioglu, Ali& Comez, Mehmet…[et al.]. Is Infusion of Subhypnotic Propofol as Effective as Dexamethasone in Prevention of Postoperative Nausea and Vomiting Related to Laparoscopic Cholecystectomy? A Randomized Controlled Trial. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1055146
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055146