Primary Retinal Cultures as a Tool for Modeling Diabetic Retinopathy: An Overview
Joint Authors
Matteucci, Andrea
Varano, Monica
Mallozzi, Cinzia
Gaddini, Lucia
Villa, Marika
Gabrielli, Sara
Formisano, Giuseppe
Pricci, Flavia
Malchiodi-Albedi, Fiorella
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-19
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Experimental models of diabetic retinopathy (DR) have had a crucial role in the comprehension of the pathophysiology of the disease and the identification of new therapeutic strategies.
Most of these studies have been conducted in vivo, in animal models.
However, a significant contribution has also been provided by studies on retinal cultures, especially regarding the effects of the potentially toxic components of the diabetic milieu on retinal cell homeostasis, the characterization of the mechanisms on the basis of retinal damage, and the identification of potentially protective molecules.
In this review, we highlight the contribution given by primary retinal cultures to the study of DR, focusing on early neuroglial impairment.
We also speculate on possible themes into which studies based on retinal cell cultures could provide deeper insight.
American Psychological Association (APA)
Matteucci, Andrea& Varano, Monica& Mallozzi, Cinzia& Gaddini, Lucia& Villa, Marika& Gabrielli, Sara…[et al.]. 2015. Primary Retinal Cultures as a Tool for Modeling Diabetic Retinopathy: An Overview. BioMed Research International،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1055202
Modern Language Association (MLA)
Matteucci, Andrea…[et al.]. Primary Retinal Cultures as a Tool for Modeling Diabetic Retinopathy: An Overview. BioMed Research International No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1055202
American Medical Association (AMA)
Matteucci, Andrea& Varano, Monica& Mallozzi, Cinzia& Gaddini, Lucia& Villa, Marika& Gabrielli, Sara…[et al.]. Primary Retinal Cultures as a Tool for Modeling Diabetic Retinopathy: An Overview. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1055202
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055202