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Complete Nucleotide Sequence Analysis of the Norovirus GII.4 Sydney Variant in South Korea
Joint Authors
Lee, Sung-Geun
Jheong, Weon-Hwa
Paik, Soon-Young
Jin, Ji-Young
Park, Ji-Sun
Cho, Han-Gil
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Norovirus is the primary cause of acute gastroenteritis in individuals of all ages.
In Australia, a new strain of norovirus (GII.4) was identified in March 2012, and this strain has spread rapidly around the world.
In August 2012, this new GII.4 strain was identified in patients in South Korea.
Therefore, to examine the characteristics of the epidemic norovirus GII.4 2012 variant in South Korea, we conducted KM272334 full-length genomic analysis.
The genome of the gg-12-08-04 strain consisted of 7,558 bp and contained three open reading frame (ORF) composites throughout the whole genome: ORF1 (5,100 bp), ORF2 (1,623 bp), and ORF3 (807 bp).
Phylogenetic analyses showed that gg-12-08-04 belonged to the GII.4 Sydney 2012 variant, sharing 98.92% nucleotide similarity with this variant strain.
According to SimPlot analysis, the gg-12-08-04 strain was a recombinant strain with breakpoint at the ORF1/2 junction between Osaka 2007 and Apeldoorn 2008 strains.
This study is the first report of the complete sequence of the GII.4 Sydney 2012 strain in South Korea.
Therefore, this may represent the standard sequence of the norovirus GII.4 2012 variant in South Korea and could therefore be useful for the development of norovirus vaccines.
American Psychological Association (APA)
Park, Ji-Sun& Lee, Sung-Geun& Jin, Ji-Young& Cho, Han-Gil& Jheong, Weon-Hwa& Paik, Soon-Young. 2015. Complete Nucleotide Sequence Analysis of the Norovirus GII.4 Sydney Variant in South Korea. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055236
Modern Language Association (MLA)
Park, Ji-Sun…[et al.]. Complete Nucleotide Sequence Analysis of the Norovirus GII.4 Sydney Variant in South Korea. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1055236
American Medical Association (AMA)
Park, Ji-Sun& Lee, Sung-Geun& Jin, Ji-Young& Cho, Han-Gil& Jheong, Weon-Hwa& Paik, Soon-Young. Complete Nucleotide Sequence Analysis of the Norovirus GII.4 Sydney Variant in South Korea. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055236
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055236