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Prefrontal Hemodynamic Changes Associated with Subjective Sense of Occlusal Discomfort
Joint Authors
Ono, Yumie
Kobayashi, Goh
Hayama, Rika
Ikuta, Ryuhei
Wake, Hiroyuki
Shimada, Atsushi
Shibuya, Tomoaki
Tamaki, Katsushi
Onozuka, Minoru
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
We used functional near-infrared spectroscopy to measure prefrontal brain activity accompanying the physical sensation of oral discomfort that arose when healthy young-adult volunteers performed a grinding motion with mild occlusal elevation (96 μm).
We simultaneously evaluated various forms of occlusal discomfort using the visual analogue scale (VAS) and hemodynamic responses to identify the specific prefrontal activity that occurs with increased occlusal discomfort.
The Oxy-Hb responses of selected channels in the bilateral frontopolar and dorsolateral prefrontal cortices increased in participants who reported increased severity of occlusal discomfort, while they decreased in those who reported no change or decreased occlusal discomfort during grinding.
Moreover, the cumulative values of Oxy-Hb response in some of these channels were statistically significant predictive factors for the VAS scores.
A generalized linear model analysis of Oxy-Hb signals in a group of participants who reported increased discomfort further indicated significant cerebral activation in the right frontopolar and dorsolateral prefrontal cortices that overlapped with the results of correlation analyses.
Our results suggest that the increased hemodynamic responses in the prefrontal area reflect the top-down control of attention and/or self-regulation against the uncomfortable somatosensory input, which could be a possible marker to detect the subjective sense of occlusal discomfort.
American Psychological Association (APA)
Ono, Yumie& Kobayashi, Goh& Hayama, Rika& Ikuta, Ryuhei& Onozuka, Minoru& Wake, Hiroyuki…[et al.]. 2015. Prefrontal Hemodynamic Changes Associated with Subjective Sense of Occlusal Discomfort. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055317
Modern Language Association (MLA)
Ono, Yumie…[et al.]. Prefrontal Hemodynamic Changes Associated with Subjective Sense of Occlusal Discomfort. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1055317
American Medical Association (AMA)
Ono, Yumie& Kobayashi, Goh& Hayama, Rika& Ikuta, Ryuhei& Onozuka, Minoru& Wake, Hiroyuki…[et al.]. Prefrontal Hemodynamic Changes Associated with Subjective Sense of Occlusal Discomfort. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055317
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055317