A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies
Joint Authors
Piraino, Francesco
Selimović, Šeila
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The intricate process of wound healing involves activation of biological pathways that work in concert to regenerate a tissue microenvironment consisting of cells and external cellular matrix (ECM) with enzymes, cytokines, and growth factors.
Distinct stages characterize the mammalian response to tissue injury: hemostasis, inflammation, new tissue formation, and tissue remodeling.
Hemostasis and inflammation start right after the injury, while the formation of new tissue, along with migration and proliferation of cells within the wound site, occurs during the first week to ten days after the injury.
In this review paper, we discuss approaches in tissue engineering and regenerative medicine to address each of these processes through the application of biomaterials, either as support to the native microenvironment or as delivery vehicles for functional hemostatic, antibacterial, or anti-inflammatory agents.
Molecular therapies are also discussed with particular attention to drug delivery methods and gene therapies.
Finally, cellular treatments are reviewed, and an outlook on the future of drug delivery and wound care biomaterials is provided.
American Psychological Association (APA)
Piraino, Francesco& Selimović, Šeila. 2015. A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055351
Modern Language Association (MLA)
Piraino, Francesco& Selimović, Šeila. A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1055351
American Medical Association (AMA)
Piraino, Francesco& Selimović, Šeila. A Current View of Functional Biomaterials for Wound Care, Molecular and Cellular Therapies. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055351
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055351