Current Status of Research on Osteoporosis after Solid Organ Transplantation: Pathogenesis and Management
Joint Authors
Lan, Gong-bin
Xie, Xu-biao
Peng, Long-kai
Liu, Lei
Song, Lei
Dai, He-long
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-15
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Improved survival following organ transplantation has brought to the forefront some long-term complications, among which osteoporosis and associated fractures are the major ones that adversely affect the quality of life in recipients.
The pathogenesis of osteoporosis in transplant recipients is complex and multifactorial which may be related to increased bone resorption, decreased bone formation, or both.
Studies have shown that the preexisting underlying metabolic bone disorders and the use of immunosuppressive agents are the major risk factors for osteoporosis and fractures after organ transplantation.
And rapid bone loss usually occurs in the first 6–12 months with a significant increase in fracture risk.
This paper will provide an updated review on the possible pathogenesis of posttransplant osteoporosis and fractures, the natural history, and the current prevention and treatment strategies concerning different types of organ transplantation.
American Psychological Association (APA)
Lan, Gong-bin& Xie, Xu-biao& Peng, Long-kai& Liu, Lei& Song, Lei& Dai, He-long. 2015. Current Status of Research on Osteoporosis after Solid Organ Transplantation: Pathogenesis and Management. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055385
Modern Language Association (MLA)
Lan, Gong-bin…[et al.]. Current Status of Research on Osteoporosis after Solid Organ Transplantation: Pathogenesis and Management. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1055385
American Medical Association (AMA)
Lan, Gong-bin& Xie, Xu-biao& Peng, Long-kai& Liu, Lei& Song, Lei& Dai, He-long. Current Status of Research on Osteoporosis after Solid Organ Transplantation: Pathogenesis and Management. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055385
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055385