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Bone Regeneration from PLGA Micro-Nanoparticles
Joint Authors
Padial-Molina, Miguel
Jódar-Reyes, Ana Belén
Peula-García, Jose Manuel
Ortega-Oller, Inmaculada
Galindo-Moreno, Pablo
O'Valle, Francisco
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-05
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Poly-lactic-co-glycolic acid (PLGA) is one of the most widely used synthetic polymers for development of delivery systems for drugs and therapeutic biomolecules and as component of tissue engineering applications.
Its properties and versatility allow it to be a reference polymer in manufacturing of nano- and microparticles to encapsulate and deliver a wide variety of hydrophobic and hydrophilic molecules.
It additionally facilitates and extends its use to encapsulate biomolecules such as proteins or nucleic acids that can be released in a controlled way.
This review focuses on the use of nano/microparticles of PLGA as a delivery system of one of the most commonly used growth factors in bone tissue engineering, the bone morphogenetic protein 2 (BMP2).
Thus, all the needed requirements to reach a controlled delivery of BMP2 using PLGA particles as a main component have been examined.
The problems and solutions for the adequate development of this system with a great potential in cell differentiation and proliferation processes under a bone regenerative point of view are discussed.
American Psychological Association (APA)
Ortega-Oller, Inmaculada& Padial-Molina, Miguel& Galindo-Moreno, Pablo& O'Valle, Francisco& Jódar-Reyes, Ana Belén& Peula-García, Jose Manuel. 2015. Bone Regeneration from PLGA Micro-Nanoparticles. BioMed Research International،Vol. 2015, no. 2015, pp.1-18.
https://search.emarefa.net/detail/BIM-1055400
Modern Language Association (MLA)
Ortega-Oller, Inmaculada…[et al.]. Bone Regeneration from PLGA Micro-Nanoparticles. BioMed Research International No. 2015 (2015), pp.1-18.
https://search.emarefa.net/detail/BIM-1055400
American Medical Association (AMA)
Ortega-Oller, Inmaculada& Padial-Molina, Miguel& Galindo-Moreno, Pablo& O'Valle, Francisco& Jódar-Reyes, Ana Belén& Peula-García, Jose Manuel. Bone Regeneration from PLGA Micro-Nanoparticles. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-18.
https://search.emarefa.net/detail/BIM-1055400
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055400