TNF-Related Apoptosis Inducing Ligand in Ocular Cancers and Ocular Diabetic Complications
Joint Authors
Secchiero, Paola
Perri, Paolo
Gianesini, Sergio
Celeghini, Claudio
Gonelli, Arianna
Milani, Daniela
Zauli, Giorgio
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
TNF-related apoptosis inducing ligand (TRAIL) is an intensively studied cytokine, in particular for its anticancer activity.
The discovery that conjunctival sac fluid contains extremely high levels of soluble TRAIL as compared to other body fluids suggested important implications in the context of the immunological surveillance of the eye, in particular of the anterior surface.
In this review, we discuss the potential physiopathologic and therapeutic role of the TRAIL/TRAIL receptor system in a variety of ocular cancers.
Moreover, since an increasing amount of data has indicated the important biological activities of the TRAIL/TRAIL receptor systems also in a completely different pathologic context such as diabetes mellitus, in the second part of this review we summarize the currently available data on the involvement of TRAIL in the ocular complications of diabetes mellitus as modulator of the inflammatory and angiogenic response in the eye.
American Psychological Association (APA)
Perri, Paolo& Zauli, Giorgio& Gonelli, Arianna& Milani, Daniela& Celeghini, Claudio& Gianesini, Sergio…[et al.]. 2015. TNF-Related Apoptosis Inducing Ligand in Ocular Cancers and Ocular Diabetic Complications. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055437
Modern Language Association (MLA)
Perri, Paolo…[et al.]. TNF-Related Apoptosis Inducing Ligand in Ocular Cancers and Ocular Diabetic Complications. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1055437
American Medical Association (AMA)
Perri, Paolo& Zauli, Giorgio& Gonelli, Arianna& Milani, Daniela& Celeghini, Claudio& Gianesini, Sergio…[et al.]. TNF-Related Apoptosis Inducing Ligand in Ocular Cancers and Ocular Diabetic Complications. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055437
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055437