Immunoendocrine Interactions during HIV-TB Coinfection: Implications for the Design of New Adjuvant Therapies
Joint Authors
Suarez, Guadalupe Veronica
Vecchione, Maria Belen
Angerami, Matias Tomas
Sued, Omar
Bruttomesso, Andrea Claudia
Bottasso, Oscar Adelmo
Quiroga, Maria Florencia
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Worldwide, around 14 million individuals are coinfected with both tuberculosis (TB) and human immunodeficiency virus (HIV).
In coinfected individuals, both pathogens weaken immunological system synergistically through mechanisms that are not fully understood.
During both HIV and TB infections, there is a chronic state of inflammation associated to dramatic changes in immune cytokine and endocrine hormone levels.
Despite this, the relevance of immunoendocrine interaction on both the orchestration of an effective immune response against both pathogens and the control of the chronic inflammation induced during HIV, TB, or both infections is still controversial.
The present study reviews immunoendocrine interactions occurring during HIV and TB infections.
We also expose our own findings on immunoendocrine cross talk in HIV-TB coinfection.
Finally, we evaluate the use of adrenal hormones and their derivatives in immune-therapy and discuss the use of some of these compounds like the adjuvant for the prevention and treatment of TB in HIV patients.
American Psychological Association (APA)
Suarez, Guadalupe Veronica& Vecchione, Maria Belen& Angerami, Matias Tomas& Sued, Omar& Bruttomesso, Andrea Claudia& Bottasso, Oscar Adelmo…[et al.]. 2015. Immunoendocrine Interactions during HIV-TB Coinfection: Implications for the Design of New Adjuvant Therapies. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055566
Modern Language Association (MLA)
Suarez, Guadalupe Veronica…[et al.]. Immunoendocrine Interactions during HIV-TB Coinfection: Implications for the Design of New Adjuvant Therapies. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1055566
American Medical Association (AMA)
Suarez, Guadalupe Veronica& Vecchione, Maria Belen& Angerami, Matias Tomas& Sued, Omar& Bruttomesso, Andrea Claudia& Bottasso, Oscar Adelmo…[et al.]. Immunoendocrine Interactions during HIV-TB Coinfection: Implications for the Design of New Adjuvant Therapies. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055566
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055566