Prevalence of Nontuberculous Mycobacteria among Extrapulmonary Tuberculosis Cases in Tertiary Care Centers in Northern India
Joint Authors
Maurya, A. K.
Nag, V. L.
Kant, S.
Kushwaha, R. A. S.
Kumar, M.
Singh, A. K.
Dhole, T. N.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The reports of nontuberculous mycobacteria (NTM) associated with extrapulmonary diseases are increasing in tertiary care hospitals.
Despite a significant increase in knowledge about NTM infections, they still represent a diagnostic and therapeutic challenge.
The aim of this study is to know the prevalence of NTN among extrapulmonary tuberculosis cases in tertiary care centers in Northern India.
A total of 227 culture positive isolates from 756 cases were tested for niacin production and catalase assay.
BIO-LINE SD Ag MPT64 TB test and final identification and differentiation between MTBC and different species of NTM were further confirmed by GenoType Mycobacterium CM/AS assay.
71 cases (9.3%) were positive for AFB by ZN staining and 227 cases (30.1%) were positive for mycobacteria by culture.
Niacin production and catalase activity were negative in 62/227 (27.4%) strains and after using a panel of different biochemicals and final confirmation by GenoType Mycobacterium CM assay.
Out of 227 cultures tested, 165 (72.6%) strains were confirmed as M.
tuberculosis complex, and 62 (27.4%) were confirmed as NTM.
The most common NTM species identified were M.
fortuitum 17 (27.5%) and M.
intracellulare 13 (20.9%).
The rapid identification of NTM species may help in targeted therapy and management of the diseases.
American Psychological Association (APA)
Maurya, A. K.& Nag, V. L.& Kant, S.& Kushwaha, R. A. S.& Kumar, M.& Singh, A. K.…[et al.]. 2015. Prevalence of Nontuberculous Mycobacteria among Extrapulmonary Tuberculosis Cases in Tertiary Care Centers in Northern India. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1055582
Modern Language Association (MLA)
Maurya, A. K.…[et al.]. Prevalence of Nontuberculous Mycobacteria among Extrapulmonary Tuberculosis Cases in Tertiary Care Centers in Northern India. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1055582
American Medical Association (AMA)
Maurya, A. K.& Nag, V. L.& Kant, S.& Kushwaha, R. A. S.& Kumar, M.& Singh, A. K.…[et al.]. Prevalence of Nontuberculous Mycobacteria among Extrapulmonary Tuberculosis Cases in Tertiary Care Centers in Northern India. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1055582
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055582