Ocular Surface and Tear Film Changes in Older Women Working with Computers
Joint Authors
Diaz-Llopis, Manuel
Ribelles, Alfredo
Parras, Maria A.
Marco-Ramírez, Carla
Galbis-Estrada, Carmen
Vivar-Llopis, Bárbara
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-18
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The aim of this work is to investigate changes in the ocular surface (OS) and tear film (TF) by means of questionnaire-based subjective symptoms, TF break-up time, Schirmer test, and TF analysis in women working with computers and to analyze the effects of the oral supplementation with antioxidants/omega 3 fatty acids (A/ω3) in the OS outcomes.
Women aged 40–65 years ( n = 148 ) were recruited at the Administrative Offices of Valencia (Spain) and distributed into two age groups, 40–52 years (AGE1; n = 87 ) and 53–65 years (AGE2; n = 61 ), and then subdivided according to being (or not) computer users (CUG; NCUG) during the workday.
Homogeneous subgroups were randomly assigned (or not) to the daily intake of three pills of A/ω3 for three months.
At baseline and at the end of follow-up, personalized interviews and ocular examination were done.
Reflex tear samples were collected from the inferior meniscus and processed for a multiplexed particle-based flow cytometry assay to measure proinflammatory molecules.
Statistics were performed using the SPSS 15.0 program.
The OS pathology was clinically evident in the AGE1-CUG (33%) versus the AGE2-CUG (64%) of women.
Significantly higher interleukins-1β and -6 tear levels were found in the AGE1 versus the AGE2 women employees ( P = 0.006 and P = 0.001 , resp.), as well as in the CUG versus the NCUG ( P = 0.001 and P = 0.000 , resp.).
Supplementation with A/ω3 positively influenced the OS pathology as manifested by the amelioration of the clinical signs/symptoms related to computer uses.
Strategies involving a safe environment and oral micronutrient supplements may be managed within eye-care standards in older women.
American Psychological Association (APA)
Ribelles, Alfredo& Galbis-Estrada, Carmen& Parras, Maria A.& Vivar-Llopis, Bárbara& Marco-Ramírez, Carla& Diaz-Llopis, Manuel. 2015. Ocular Surface and Tear Film Changes in Older Women Working with Computers. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055587
Modern Language Association (MLA)
Ribelles, Alfredo…[et al.]. Ocular Surface and Tear Film Changes in Older Women Working with Computers. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1055587
American Medical Association (AMA)
Ribelles, Alfredo& Galbis-Estrada, Carmen& Parras, Maria A.& Vivar-Llopis, Bárbara& Marco-Ramírez, Carla& Diaz-Llopis, Manuel. Ocular Surface and Tear Film Changes in Older Women Working with Computers. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055587
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055587