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Outcomes of Intracytoplasmic Sperm Injection Cycles for Complete Teratozoospermia: A Case-Control Study Using Paired Sibling Oocytes
Joint Authors
Pereira, Nigel
Neri, Queenie V.
Lekovich, Jovana P.
Spandorfer, Steven D.
Palermo, Gianpiero D.
Rosenwaks, Zev
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To investigate the outcomes of intracytoplasmic sperm injection (ICSI) cycles where sibling oocytes from a single donor were split between two recipients based on strict sperm morphology.
Methods.
Retrospective cohort study.
All ICSI cycles had one donor’s oocytes split between two recipients in a 1 : 1 ratio based on strict sperm morphology, that is, one male partner had morphology of 0% and the other had morphology of >1%.
Fertilization, positive hCG, clinical pregnancy, spontaneous miscarriage, and live birth rates of the aforementioned groups were compared.
Results.
The baseline characteristics of the two groups (n=103), including semen parameters of the male partners, were comparable.
There was no difference in the fertilization rates when comparing the 0% group to the >1% group (78.7% versus 81.6%; P=0.66).
The overall positive hCG, clinical pregnancy, spontaneous miscarriage, and live birth rates for the 0% group were 61.2%, 49.5%, 10.7%, and 38.8%, respectively.
The corresponding rates in the >1% group were positive hCG (63.1%), clinical pregnancy (55.3%), spontaneous miscarriage (7.77%), and live birth (46.6%).
Conclusions.
The fertilization and pregnancy outcomes of ICSI cycles for strict sperm morphology of 0% versus morphology of >1% are equivalent.
These results can provide reassurance to couples undergoing ICSI for severe teratospermia.
American Psychological Association (APA)
Pereira, Nigel& Neri, Queenie V.& Lekovich, Jovana P.& Spandorfer, Steven D.& Palermo, Gianpiero D.& Rosenwaks, Zev. 2015. Outcomes of Intracytoplasmic Sperm Injection Cycles for Complete Teratozoospermia: A Case-Control Study Using Paired Sibling Oocytes. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1055603
Modern Language Association (MLA)
Pereira, Nigel…[et al.]. Outcomes of Intracytoplasmic Sperm Injection Cycles for Complete Teratozoospermia: A Case-Control Study Using Paired Sibling Oocytes. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1055603
American Medical Association (AMA)
Pereira, Nigel& Neri, Queenie V.& Lekovich, Jovana P.& Spandorfer, Steven D.& Palermo, Gianpiero D.& Rosenwaks, Zev. Outcomes of Intracytoplasmic Sperm Injection Cycles for Complete Teratozoospermia: A Case-Control Study Using Paired Sibling Oocytes. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1055603
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055603