A Large-Scale Structural Classification of Antimicrobial Peptides
Joint Authors
Lee, Hao-Ting
Lee, Chen-Che
Yang, Je-Ruei
Lai, Jim Z. C.
Chang, Kuan Y.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Antimicrobial peptides (AMPs) are potent drug candidates against microbial organisms such as bacteria, fungi, parasites, and viruses.
AMPs have abundant sequences and structures, two fundamental resources for bioinformatics researches, but analyses on how they associate with each other are either nonexistent or limited to partial classification and data.
We thus present A Database of Anti-Microbial peptides (ADAM), which contains 7,007 unique sequences and 759 structures, to systematically establish comprehensive associations between AMP sequences and structures through structural folds and to provide an easy access to view their relationships.
30 distinct AMP structural fold clusters with more than one structure are detected and about a thousand AMPs are associated with at least one structural fold cluster.
According to ADAM, AMP structural folds are limited—AMPs only cover about 3% of the overall protein fold space.
American Psychological Association (APA)
Lee, Hao-Ting& Lee, Chen-Che& Yang, Je-Ruei& Lai, Jim Z. C.& Chang, Kuan Y.. 2015. A Large-Scale Structural Classification of Antimicrobial Peptides. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1055615
Modern Language Association (MLA)
Lee, Hao-Ting…[et al.]. A Large-Scale Structural Classification of Antimicrobial Peptides. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1055615
American Medical Association (AMA)
Lee, Hao-Ting& Lee, Chen-Che& Yang, Je-Ruei& Lai, Jim Z. C.& Chang, Kuan Y.. A Large-Scale Structural Classification of Antimicrobial Peptides. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1055615
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055615