Contrast-Enhanced Endoscopic Ultrasonography for Pancreatic Tumors
Joint Authors
Iguchi, Mikitaka
Tamai, Hideyuki
Maekita, Takao
Ueda, Kazuki
Yamashita, Yasunobu
Kato, Jun
Kawaji, Yuki
Abe, Hiroko
Nuta, Junya
Tamura, Takashi
Itonaga, Masahiro
Yoshida, Takeichi
Maeda, Hiroki
Ichinose, Masao
Nakamura, Yasushi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objectives.
To investigate the usefulness of contrast-enhanced endoscopic ultrasonography (CE-EUS) for histological differentiation of pancreatic tumors.
Methods.
CE-EUS was performed for consecutive patients having a pancreatic solid lesion, and tumors were classified into three vascular patterns (hypervascular, isovascular, and hypovascular) at two time phases (early-phase and late-phase).
Correlation between vascular patterns and histopathology of resected pancreatic cancer (PC) tissues was ascertained.
Results.
The final diagnoses of 147 examined tumors were PC ( n = 109 ) , inflammatory mass ( n = 11 ) , autoimmune pancreatitis ( n = 9 ) , neuroendocrine tumor ( n = 8 ) , and others ( n = 10 ) .
In late-phase images, 104 of 109 PCs had the hypovascular pattern, for a diagnostic sensitivity and specificity of 94% and 71%, respectively.
Of 28 resected PCs, 10 had isovascular, and 18 hypovascular, patterns on the early-phase image.
Early-phase isovascular PCs were more likely to be differentiated than were early-phase hypovascular PCs (6 well and 4 moderately differentiated versus 3 well, 14 moderately, and 1 poorly differentiated, P = 0.028 ) .
Immunostaining revealed that hypovascular areas of early-phase images reflected heterogeneous tumor cells with fibrous tissue, necrosis, and few vessels.
Conclusion.
CE-EUS could be useful for distinguishing PC from other solid pancreatic lesions and for histological differentiation of PCs.
American Psychological Association (APA)
Yamashita, Yasunobu& Kato, Jun& Ueda, Kazuki& Nakamura, Yasushi& Kawaji, Yuki& Abe, Hiroko…[et al.]. 2015. Contrast-Enhanced Endoscopic Ultrasonography for Pancreatic Tumors. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055685
Modern Language Association (MLA)
Yamashita, Yasunobu…[et al.]. Contrast-Enhanced Endoscopic Ultrasonography for Pancreatic Tumors. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1055685
American Medical Association (AMA)
Yamashita, Yasunobu& Kato, Jun& Ueda, Kazuki& Nakamura, Yasushi& Kawaji, Yuki& Abe, Hiroko…[et al.]. Contrast-Enhanced Endoscopic Ultrasonography for Pancreatic Tumors. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055685
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055685