Radiological Imaging for Assessing the Respectability of Hilar Cholangiocarcinoma: A Systematic Review and Meta-Analysis
Joint Authors
Zhang, Hongchen
Zhu, Jian
Ke, Fayong
Weng, Mingzhe
Wu, Xiangsong
Li, Maolan
Quan, Zhiwei
Liu, Yingbin
Zhang, Yong
Gong, Wei
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-01
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Hilar cholangiocarcinoma (HCC) remains one of the most difficult tumors to stage and treat.
The aim of the study was to assess the diagnostic efficiency of computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computer tomography (PET/CT) in evaluating the resectability of HCC.
A systematic search was performed of the PubMed, EMBASE, and Cochrane databases.
Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy were calculated for individual studies and pooled data as well as test for heterogeneity and public bias.
Our data showed that CT had the highest pooled sensitivity at 95% (95% CI: 91–97), whereas PET/CT had the highest pooled specificity at 81% (95% CI: 69–90).
The area under the curve (AUC) of CT, MRI, and PET/CT was 0.9269, 0.9194, and 0.9218, respectively.
In conclusion, CT is the most frequently used imaging modality to assess HCC resectability with a good sensitivity and specificity.
MRI was generally comparable with that of CT and can be used as an alternative imaging technique.
PET/CT appears to be the best technique in detecting lymph node and distant metastasis in HCC but has no clear role in helping to evaluate issues of local resectability.
American Psychological Association (APA)
Zhang, Hongchen& Zhu, Jian& Ke, Fayong& Weng, Mingzhe& Wu, Xiangsong& Li, Maolan…[et al.]. 2015. Radiological Imaging for Assessing the Respectability of Hilar Cholangiocarcinoma: A Systematic Review and Meta-Analysis. BioMed Research International،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1055707
Modern Language Association (MLA)
Zhang, Hongchen…[et al.]. Radiological Imaging for Assessing the Respectability of Hilar Cholangiocarcinoma: A Systematic Review and Meta-Analysis. BioMed Research International No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1055707
American Medical Association (AMA)
Zhang, Hongchen& Zhu, Jian& Ke, Fayong& Weng, Mingzhe& Wu, Xiangsong& Li, Maolan…[et al.]. Radiological Imaging for Assessing the Respectability of Hilar Cholangiocarcinoma: A Systematic Review and Meta-Analysis. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1055707
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055707