T Lymphocyte Dynamics in Inflammatory Bowel Diseases: Role of the Microbiome
Joint Authors
Larmonier, C. B.
Shehab, K. W.
Ghishan, F. K.
Kiela, P. R.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Humans have coevolved with a complex community of bacterial species also referred to as the microbiome, which reciprocally provides critical contributions to human metabolism and immune system development.
Gut microbiome composition differs significantly between individuals depending on host genetics, diet, and environmental factors.
A dysregulation of the symbiotic nature of the intestinal host-microbial relationship and an aberrant and persistent immune response are the fundamental processes involved in inflammatory bowel diseases (IBD).
Considering the essential role of T cells in IBD and the contributing role of the microbiome in shaping the immune response during the pathogenesis of IBD, this review focuses on the complex relationship, interplay, and communication between the gut microbiome and T cells, including their differentiation into different subsets of effector or regulatory cells.
American Psychological Association (APA)
Larmonier, C. B.& Shehab, K. W.& Ghishan, F. K.& Kiela, P. R.. 2015. T Lymphocyte Dynamics in Inflammatory Bowel Diseases: Role of the Microbiome. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055725
Modern Language Association (MLA)
Larmonier, C. B.…[et al.]. T Lymphocyte Dynamics in Inflammatory Bowel Diseases: Role of the Microbiome. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1055725
American Medical Association (AMA)
Larmonier, C. B.& Shehab, K. W.& Ghishan, F. K.& Kiela, P. R.. T Lymphocyte Dynamics in Inflammatory Bowel Diseases: Role of the Microbiome. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055725
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055725