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Micro- and Nanosized Particles in Nasal Mucosa: A Pilot Study
Joint Authors
Čábalová, Lenka
Čabanová, Kristina
Bielniková, Hana
Kukutschová, Jana
Dvořáčková, Jana
Dědková, Kateřina
Zeleník, Karol
Kominek, Pavel
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
The aim of this prospective study is to evaluate presence and quantity of micro- and nanosized particles (NPs) and interindividual differences in their distribution and composition in nasal mucosa.
Methods.
Six samples of nasal mucosa obtained by mucotomy from patients with chronic hypertrophic rhinosinusitis were examined.
Samples divided into 4 parts according to the distance from the nostrils were analyzed by scanning electron microscopy and Raman microspectroscopy to detect solid particles and characterize their morphology and composition.
A novel method of quantification of the particles was designed and used to evaluate interindividual differences in distribution of the particles.
The findings were compared with patients’ employment history.
Results.
In all the samples, NPs of different elemental composition were found (iron, barium, copper, titanium, etc.), predominantly in the parts most distant from nostrils, in various depths from the surface of the mucosa and interindividual differences in their quantity and composition were found, possibly in relation to professional exposition.
Conclusions.
This study has proven the possibility of quantification of distribution of micro- and nanosized particles in tissue samples and that the NPs may deposit in deeper layers of mucosa and their elemental composition may be related to professional exposition to the sources of NPs.
American Psychological Association (APA)
Čábalová, Lenka& Čabanová, Kristina& Bielniková, Hana& Kukutschová, Jana& Dvořáčková, Jana& Dědková, Kateřina…[et al.]. 2015. Micro- and Nanosized Particles in Nasal Mucosa: A Pilot Study. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1055735
Modern Language Association (MLA)
Čábalová, Lenka…[et al.]. Micro- and Nanosized Particles in Nasal Mucosa: A Pilot Study. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1055735
American Medical Association (AMA)
Čábalová, Lenka& Čabanová, Kristina& Bielniková, Hana& Kukutschová, Jana& Dvořáčková, Jana& Dědková, Kateřina…[et al.]. Micro- and Nanosized Particles in Nasal Mucosa: A Pilot Study. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1055735
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055735