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Swimming Activity Prevents the Unloading Induced Loss of Bone Mass, Architecture, and Strength in Rats
Joint Authors
Volpon, José Batista
Falcai, Maurício J.
Leoni, Graziela Bianchi
Sousa-Neto, Manoel Damião
Zamarioli, Ariane
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We investigated whether swimming activity associated with a three-week period of hypoactivity could prevent the deleterious effects of disuse on the tibias of tail-suspended rats.
Forty Wistar rats were divided into five groups: (HS) permanently hindlimb suspension rats; (HS + Swim) rats submitted to unloading interrupted by swimming exercise; (HS + WB) hindlimb suspension rats with interruption for regular weight bearing for the same length of time as the HS+Swim rats; (Control) control rats that were allowed regular cage activities; and (Control + Swim) control rats that underwent swimming exercise.
At the end of the experiment, bone mineral density, bone strength, and trabecular quantification were analyzed.
The hindlimb-suspended rats exhibited bone quality loss (significant decrease in BMD, bone strength, and deterioration of trabecular and cortical bone architecture; decrease in BV/TV, TbN, TbTh, ConnD, CtV, and CtTh; and increase in TbSp) when compared to control rats.
In contrast, trained rats showed a significant increase of 43% in bone mass, 29% in bone strength, 58% in trabecular thickness, 85% in bone volume, 27% in trabeculae number, and 30% in cortical volume, when compared to the hindlimb-suspended rats.
We conclude that swimming activity not only ameliorates but also fully prevents the deleterious effects on bone quality in osteopenic rats.
American Psychological Association (APA)
Falcai, Maurício J.& Zamarioli, Ariane& Leoni, Graziela Bianchi& Sousa-Neto, Manoel Damião& Volpon, José Batista. 2015. Swimming Activity Prevents the Unloading Induced Loss of Bone Mass, Architecture, and Strength in Rats. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055745
Modern Language Association (MLA)
Falcai, Maurício J.…[et al.]. Swimming Activity Prevents the Unloading Induced Loss of Bone Mass, Architecture, and Strength in Rats. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1055745
American Medical Association (AMA)
Falcai, Maurício J.& Zamarioli, Ariane& Leoni, Graziela Bianchi& Sousa-Neto, Manoel Damião& Volpon, José Batista. Swimming Activity Prevents the Unloading Induced Loss of Bone Mass, Architecture, and Strength in Rats. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055745
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055745