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Monoamine Oxidases as Potential Contributors to Oxidative Stress in Diabetes: Time for a Study in Patients Undergoing Heart Surgery
Joint Authors
Duicu, Oana M.
Lighezan, Rodica
Sturza, Adrian
Ceausu, Raluca A.
Borza, Claudia
Vaduva, Adrian
Noveanu, Lavinia
Gaspar, Marian
Ionac, Adina
Feier, Horea
Muntean, Danina M.
Mornos, Cristian
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Oxidative stress is a pathomechanism causally linked to the progression of chronic cardiovascular diseases and diabetes.
Mitochondria have emerged as the most relevant source of reactive oxygen species, the major culprit being classically considered the respiratory chain at the inner mitochondrial membrane.
In the past decade, several experimental studies unequivocally demonstrated the contribution of monoamine oxidases (MAOs) at the outer mitochondrial membrane to the maladaptative ventricular hypertrophy and endothelial dysfunction.
This paper addresses the contribution of mitochondrial dysfunction to the pathogenesis of heart failure and diabetes together with the mounting evidence for an emerging role of MAO inhibition as putative cardioprotective strategy in both conditions.
American Psychological Association (APA)
Duicu, Oana M.& Lighezan, Rodica& Sturza, Adrian& Ceausu, Raluca A.& Borza, Claudia& Vaduva, Adrian…[et al.]. 2015. Monoamine Oxidases as Potential Contributors to Oxidative Stress in Diabetes: Time for a Study in Patients Undergoing Heart Surgery. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055781
Modern Language Association (MLA)
Duicu, Oana M.…[et al.]. Monoamine Oxidases as Potential Contributors to Oxidative Stress in Diabetes: Time for a Study in Patients Undergoing Heart Surgery. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1055781
American Medical Association (AMA)
Duicu, Oana M.& Lighezan, Rodica& Sturza, Adrian& Ceausu, Raluca A.& Borza, Claudia& Vaduva, Adrian…[et al.]. Monoamine Oxidases as Potential Contributors to Oxidative Stress in Diabetes: Time for a Study in Patients Undergoing Heart Surgery. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055781
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055781