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Animal Models in Cardiovascular Research: Hypertension and Atherosclerosis
Joint Authors
Ng, Chun-Yi
Leong, Xin-Fang
Jaarin, Kamsiah
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-03
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Hypertension and atherosclerosis are among the most common causes of mortality in both developed and developing countries.
Experimental animal models of hypertension and atherosclerosis have become a valuable tool for providing information on etiology, pathophysiology, and complications of the disease and on the efficacy and mechanism of action of various drugs and compounds used in treatment.
An animal model has been developed to study hypertension and atherosclerosis for several reasons.
Compared to human models, an animal model is easily manageable, as compounding effects of dietary and environmental factors can be controlled.
Blood vessels and cardiac tissue samples can be taken for detailed experimental and biomolecular examination.
Choice of animal model is often determined by the research aim, as well as financial and technical factors.
A thorough understanding of the animal models used and complete analysis must be validated so that the data can be extrapolated to humans.
In conclusion, animal models for hypertension and atherosclerosis are invaluable in improving our understanding of cardiovascular disease and developing new pharmacological therapies.
American Psychological Association (APA)
Leong, Xin-Fang& Ng, Chun-Yi& Jaarin, Kamsiah. 2015. Animal Models in Cardiovascular Research: Hypertension and Atherosclerosis. BioMed Research International،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1055833
Modern Language Association (MLA)
Leong, Xin-Fang…[et al.]. Animal Models in Cardiovascular Research: Hypertension and Atherosclerosis. BioMed Research International No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1055833
American Medical Association (AMA)
Leong, Xin-Fang& Ng, Chun-Yi& Jaarin, Kamsiah. Animal Models in Cardiovascular Research: Hypertension and Atherosclerosis. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1055833
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055833