Glutamine: An Obligatory Parenteral Nutrition Substrate in Critical Care Therapy
Joint Authors
Stehle, Peter
Kuhn, Katharina S.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Critical illness is characterized by glutamine depletion owing to increased metabolic demand.
Glutamine is essential to maintain intestinal integrity and function, sustain immunologic response, and maintain antioxidative balance.
Insufficient endogenous availability of glutamine may impair outcome in critically ill patients.
Consequently, glutamine has been considered to be a conditionally essential amino acid and a necessary component to complete any parenteral nutrition regimen.
Recently, this scientifically sound recommendation has been questioned, primarily based on controversial findings from a large multicentre study published in 2013 that evoked considerable uncertainty among clinicians.
The present review was conceived to clarify the most important questions surrounding glutamine supplementation in critical care.
This was achieved by addressing the role of glutamine in the pathophysiology of critical illness, summarizing recent clinical studies in patients receiving parenteral nutrition with intravenous glutamine, and describing practical concepts for providing parenteral glutamine in critical care.
American Psychological Association (APA)
Stehle, Peter& Kuhn, Katharina S.. 2015. Glutamine: An Obligatory Parenteral Nutrition Substrate in Critical Care Therapy. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055894
Modern Language Association (MLA)
Stehle, Peter& Kuhn, Katharina S.. Glutamine: An Obligatory Parenteral Nutrition Substrate in Critical Care Therapy. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1055894
American Medical Association (AMA)
Stehle, Peter& Kuhn, Katharina S.. Glutamine: An Obligatory Parenteral Nutrition Substrate in Critical Care Therapy. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055894
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055894