Diverse Roles of Heparan Sulfate and Heparin in Wound Repair
Joint Authors
Olczyk, Pawel
Mencner, Łukasz
Komosinska-Vassev, Katarzyna
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Heparan sulfate (HS) and heparin (Hp) are linear polysaccharide chains composed of repeating (1 → 4) linked pyrosulfuric acid and 2-amino-2-deoxy glucopyranose (glucosamine) residue.
Mentioned glycosaminoglycans chains are covalently O-linked to serine residues within the core proteins creating heparan sulfate/heparin proteoglycans (HSPG).
The latter ones participate in many physiological and pathological phenomena impacting both the plethora of ligands such as cytokines, growth factors, and adhesion molecules and the variety of the ECM constituents.
Moreover, HS/Hp determine the effective wound healing process.
Initial growth of HS and Hp amount is pivotal during the early phase of tissue repair; however heparan sulfate and heparin also participate in further stages of tissue regeneration.
American Psychological Association (APA)
Olczyk, Pawel& Mencner, Łukasz& Komosinska-Vassev, Katarzyna. 2015. Diverse Roles of Heparan Sulfate and Heparin in Wound Repair. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055909
Modern Language Association (MLA)
Olczyk, Pawel…[et al.]. Diverse Roles of Heparan Sulfate and Heparin in Wound Repair. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1055909
American Medical Association (AMA)
Olczyk, Pawel& Mencner, Łukasz& Komosinska-Vassev, Katarzyna. Diverse Roles of Heparan Sulfate and Heparin in Wound Repair. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055909
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055909