![](/images/graphics-bg.png)
Acoustic Coordinated Reset Neuromodulation in a Real Life Patient Population with Chronic Tonal Tinnitus
Joint Authors
Langguth, Berthold
Hauptmann, Christian
Ströbel, Armin
Williams, Mark
Patel, Nitesh
Wurzer, Hannes
von Stackelberg, Tatjana
Brinkmann, Uwe
Tass, Peter A.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
Primary tinnitus has a severe negative influence on the quality of life of a significant portion of the general population.
Acoustic coordinated reset neuromodulation is designed to induce a long-lasting reduction of tinnitus symptoms.
To test acoustic coordinated reset neuromodulation as a treatment for chronic, tonal tinnitus under real life conditions, an outpatient study “RESET Real Life” was commissioned by ANM GmbH.
Herein we present the results of this study.
Methods.
In a prospective, open-label, nonrandomized, noncontrolled multicenter clinical study with 200 chronic tinnitus patients, tinnitus questionnaire TBF-12 and Global Clinical Improvement-Impression Scale (CGI-I7) are used to study the safety and efficacy of acoustic coordinated reset neuromodulation.
189 patients completed the last 12-month visit, 11 patients dropped out (8 because of nontreatment related reasons; 2 because tinnitus did not change; and 1 because tinnitus got louder).
Results.
Acoustic coordinated reset neuromodulation caused a statistically and clinically significant decrease in TBF-12 scores as well as in CGI-I7 after 12 months of therapy under real life conditions.
There were no persistent adverse events reported that were related to the therapy.
Conclusion.
The field study “RESET Real Life” provides evidence for safety and efficacy of acoustic coordinated reset neuromodulation in a prospective, open-label, real life setting.
American Psychological Association (APA)
Hauptmann, Christian& Ströbel, Armin& Williams, Mark& Patel, Nitesh& Wurzer, Hannes& von Stackelberg, Tatjana…[et al.]. 2015. Acoustic Coordinated Reset Neuromodulation in a Real Life Patient Population with Chronic Tonal Tinnitus. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055943
Modern Language Association (MLA)
Hauptmann, Christian…[et al.]. Acoustic Coordinated Reset Neuromodulation in a Real Life Patient Population with Chronic Tonal Tinnitus. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1055943
American Medical Association (AMA)
Hauptmann, Christian& Ströbel, Armin& Williams, Mark& Patel, Nitesh& Wurzer, Hannes& von Stackelberg, Tatjana…[et al.]. Acoustic Coordinated Reset Neuromodulation in a Real Life Patient Population with Chronic Tonal Tinnitus. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055943
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055943