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Intraoperative Optical Coherence Tomography Using the RESCAN 700: Preliminary Results in Collagen Crosslinking
Joint Authors
Shetty, Rohit
Nuijts, Rudy M. M. A.
Arora, Vishal
Jayadev, Chaitra
Pahuja, Natasha Kishore
Hedge, Bharath
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To compare the penetration of riboflavin using a microscope-integrated real time spectral domain optical coherence tomography (ZEISS OPMI LUMERA 700 and ZEISS RESCAN 700) in keratoconus patients undergoing accelerated collagen crosslinking (ACXL) between epithelium on (epi-on) and epithelium off (epi-off).
Methods.
Intraoperative images were obtained during each of the procedures.
Seven keratoconus patients underwent epi-on ACXL and four underwent epi-off ACXL.
A software tool was developed using Microsoft.NET and Open Computer Vision (OpenCV) libraries for image analysis.
Pre- and postprocedure images were analyzed for changes in the corneal hyperreflectance pattern as a measure of the depth of riboflavin penetration.
Results.
The mean corneal hyperreflectance in the epi-on group was 12.97 ± 1.49 gray scale units (GSU) before instillation of riboflavin and 14.46 ± 2.09 GSU after AXCL (P = 0.019) while in the epi-off group it was 11.43 ± 2.68 GSU and 16.98 ± 8.49 GSU, respectively (P = 0.002).
The average depth of the band of hyperreflectance in the epi-on group was 149.39 ± 15.63 microns and in the epi-off group it was 191.04 ± 32.18 microns.
Conclusion.
This novel in vivo, real time imaging study demonstrates riboflavin penetration during epi-on and epi-off ACXL.
American Psychological Association (APA)
Pahuja, Natasha Kishore& Shetty, Rohit& Jayadev, Chaitra& Nuijts, Rudy M. M. A.& Hedge, Bharath& Arora, Vishal. 2015. Intraoperative Optical Coherence Tomography Using the RESCAN 700: Preliminary Results in Collagen Crosslinking. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055961
Modern Language Association (MLA)
Pahuja, Natasha Kishore…[et al.]. Intraoperative Optical Coherence Tomography Using the RESCAN 700: Preliminary Results in Collagen Crosslinking. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1055961
American Medical Association (AMA)
Pahuja, Natasha Kishore& Shetty, Rohit& Jayadev, Chaitra& Nuijts, Rudy M. M. A.& Hedge, Bharath& Arora, Vishal. Intraoperative Optical Coherence Tomography Using the RESCAN 700: Preliminary Results in Collagen Crosslinking. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1055961
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055961