Kinetics of Highly Sensitive Troponin T after Cardiac Surgery
Joint Authors
Singh, Rajvir
Omar, Amr S.
Sudarsanan, Suraj
Hanoura, Samy
Osman, Hany
Sivadasan, Praveen C.
Shouman, Yasser
Tuli, Alejandro Kohn
Al Khulaifi, Abdulaziz
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Perioperative myocardial infarction (PMI) confers a considerable risk in cardiac surgery settings; finding the ideal biomarker seems to be an ideal goal.
Our aim was to assess the diagnostic accuracy of highly sensitive troponin T (hsTnT) in cardiac surgery settings and to define a diagnostic level for PMI diagnosis.
This was a single-center prospective observational study analyzing data from all patients who underwent cardiac surgeries.
The primary outcome was the diagnosis of PMI through a specific level.
The secondary outcome measures were the lengths of mechanical ventilation (LOV), stay in the intensive care unit (LOSICU), and hospitalization.
Based on the third universal definition of PMI, patients were divided into two groups: no PMI (Group I) and PMI (Group II).
Data from 413 patients were analyzed.
Nine patients fulfilled the diagnostic criteria of PMI, while 41 patients were identified with a 5-fold increase in their CK-MB (≥120 U/L).
Using ROC analysis, a hsTnT level of 3,466 ng/L or above showed 90% sensitivity and 90% specificity for the diagnosis of PMI.
Secondary outcome measures in patients with PMI were significantly prolonged.
In conclusion, the hsTnT levels detected here paralleled those of CK-MB and a cut-off level of 3466 ng/L could be diagnostic of PMI.
American Psychological Association (APA)
Omar, Amr S.& Sudarsanan, Suraj& Hanoura, Samy& Osman, Hany& Sivadasan, Praveen C.& Shouman, Yasser…[et al.]. 2015. Kinetics of Highly Sensitive Troponin T after Cardiac Surgery. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055970
Modern Language Association (MLA)
Omar, Amr S.…[et al.]. Kinetics of Highly Sensitive Troponin T after Cardiac Surgery. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1055970
American Medical Association (AMA)
Omar, Amr S.& Sudarsanan, Suraj& Hanoura, Samy& Osman, Hany& Sivadasan, Praveen C.& Shouman, Yasser…[et al.]. Kinetics of Highly Sensitive Troponin T after Cardiac Surgery. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1055970
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055970