Long-Term In Vitro Degradation of a High-Strength Brushite Cement in Water, PBS, and Serum Solution
Joint Authors
Ajaxon, Ingrid
Öhman, Caroline
Persson, Cecilia
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-26
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Bone loss and fractures may call for the use of bone substituting materials, such as calcium phosphate cements (CPCs).
CPCs can be degradable, and, to determine their limitations in terms of applications, their mechanical as well as chemical properties need to be evaluated over longer periods of time, under physiological conditions.
However, there is lack of data on how the in vitro degradation affects high-strength brushite CPCs over longer periods of time, that is, longer than it takes for a bone fracture to heal.
This study aimed at evaluating the long-term in vitro degradation properties of a high-strength brushite CPC in three different solutions: water, phosphate buffered saline, and a serum solution.
Microcomputed tomography was used to evaluate the degradation nondestructively, complemented with gravimetric analysis.
The compressive strength, chemical composition, and microstructure were also evaluated.
Major changes from 10 weeks onwards were seen, in terms of formation of a porous outer layer of octacalcium phosphate on the specimens with a concomitant change in phase composition, increased porosity, decrease in object volume, and mechanical properties.
This study illustrates the importance of long-term evaluation of similar cement compositions to be able to predict the material’s physical changes over a relevant time frame.
American Psychological Association (APA)
Ajaxon, Ingrid& Öhman, Caroline& Persson, Cecilia. 2015. Long-Term In Vitro Degradation of a High-Strength Brushite Cement in Water, PBS, and Serum Solution. BioMed Research International،Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1055974
Modern Language Association (MLA)
Ajaxon, Ingrid…[et al.]. Long-Term In Vitro Degradation of a High-Strength Brushite Cement in Water, PBS, and Serum Solution. BioMed Research International No. 2015 (2015), pp.1-17.
https://search.emarefa.net/detail/BIM-1055974
American Medical Association (AMA)
Ajaxon, Ingrid& Öhman, Caroline& Persson, Cecilia. Long-Term In Vitro Degradation of a High-Strength Brushite Cement in Water, PBS, and Serum Solution. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1055974
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1055974