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The Effects of TiO2 Nanodot Films with RGD Immobilization on Light-Induced Cell Sheet Technology
Joint Authors
Yu, Meng-Liu
Yu, Meng-Fei
Zhu, Li-Qin
Wang, Tian-Tian
Zhou, Yi
Wang, Hui-Ming
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-31
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Cell sheet technology is a new strategy in tissue engineering which could be possible to implant into the body without a scaffold.
In order to get an integrated cell sheet, a light-induced method via UV365 is used for cell sheet detachment from culture dishes.
In this study, we investigated the possibility of cell detachment and growth efficiency on TiO2 nanodot films with RGD immobilization on light-induced cell sheet technology.
Mouse calvaria-derived, preosteoblastic (MC3T3-E1) cells were cultured on TiO2 nanodot films with (TR) or without (TN) RGD immobilization.
After cells were cultured with or without 5.5 mW/cm2 UV365 illumination, cell morphology, cell viability, osteogenesis related RNA and protein expression, and cell detachment ability were compared, respectively.
Light-induced cell detachment was possible when cells were cultured on TR samples.
Also, cells cultured on TR samples showed better cell viability, alongside higher protein and RNA expression than on TN samples.
This study provides a new biomaterial for light-induced cell/cell sheet harvesting.
American Psychological Association (APA)
Yu, Meng-Liu& Yu, Meng-Fei& Zhu, Li-Qin& Wang, Tian-Tian& Zhou, Yi& Wang, Hui-Ming. 2015. The Effects of TiO2 Nanodot Films with RGD Immobilization on Light-Induced Cell Sheet Technology. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1056000
Modern Language Association (MLA)
Yu, Meng-Liu…[et al.]. The Effects of TiO2 Nanodot Films with RGD Immobilization on Light-Induced Cell Sheet Technology. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1056000
American Medical Association (AMA)
Yu, Meng-Liu& Yu, Meng-Fei& Zhu, Li-Qin& Wang, Tian-Tian& Zhou, Yi& Wang, Hui-Ming. The Effects of TiO2 Nanodot Films with RGD Immobilization on Light-Induced Cell Sheet Technology. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1056000
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056000