Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8
Joint Authors
Noma, Hisashi
Watanabe, Masanari
Kurai, Jun
Sano, Hiroyuki
Saito, Rumiko
Abe, Satoshi
Kimura, Yutaka
Oshimura, Mitsuo
Yamasaki, Akira
Shimizu, Eiji
Aiba, Setsuya
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The objective of the study was to investigate the influence of Asian dust storms (ADS) on pulmonary function of school children and the relationship of this effect with interleukin-8.
Morning peak expiratory flow (PEF) was measured daily in 399 children from April to May 2012 and in 384 of these children from March to May 2013.
The data were analyzed for an association between ADS events and PEF by linear mixed models.
Interleukin-8 transcriptional activity was assessed in THP-G8 cells stimulated by airborne particles collected on ADS days.
Seven ADS days were identified: April 23 and 24, 2012; March 8 to 10, 2013; and March 19 and 20, 2013.
Changes in PEF after ADS exposure were −8.17 L/min (95% confidence interval, −11.40 to −4.93) in 2012 and −1.17 L/min (−4.07 to 1.74) in 2013, and there was a significant difference between 2012 and 2013.
Interleukin-8 transcriptional activity was significantly higher in 2012 at 10.6 ± 2.9 -fold compared to 3.7 ± 0.4 in March 8 to 10, 2013, and 2.3 ± 0.2 in March 19 and 20, 2013.
The influence of ADS events on pulmonary function of children differs with each ADS event and may be related to interleukin-8 production.
American Psychological Association (APA)
Watanabe, Masanari& Noma, Hisashi& Kurai, Jun& Sano, Hiroyuki& Saito, Rumiko& Abe, Satoshi…[et al.]. 2015. Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8. BioMed Research International،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1056006
Modern Language Association (MLA)
Watanabe, Masanari…[et al.]. Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8. BioMed Research International No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1056006
American Medical Association (AMA)
Watanabe, Masanari& Noma, Hisashi& Kurai, Jun& Sano, Hiroyuki& Saito, Rumiko& Abe, Satoshi…[et al.]. Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1056006
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056006