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Diabetes and Stem Cell Function
Joint Authors
Wakabayashi, Tamami
Asashima, Makoto
Takemasa, Tohru
Fujimaki, Shin
Warashina, Masaki
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-17
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Diabetes mellitus is one of the most common serious metabolic diseases that results in hyperglycemia due to defects of insulin secretion or insulin action or both.
The present review focuses on the alterations to the diabetic neuronal tissues and skeletal muscle, including stem cells in both tissues, and the preventive effects of physical activity on diabetes.
Diabetes is associated with various nervous disorders, such as cognitive deficits, depression, and Alzheimer’s disease, and that may be caused by neural stem cell dysfunction.
Additionally, diabetes induces skeletal muscle atrophy, the impairment of energy metabolism, and muscle weakness.
Similar to neural stem cells, the proliferation and differentiation are attenuated in skeletal muscle stem cells, termed satellite cells.
However, physical activity is very useful for preventing the diabetic alteration to the neuronal tissues and skeletal muscle.
Physical activity improves neurogenic capacity of neural stem cells and the proliferative and differentiative abilities of satellite cells.
The present review proposes physical activity as a useful measure for the patients in diabetes to improve the physiological functions and to maintain their quality of life.
It further discusses the use of stem cell-based approaches in the context of diabetes treatment.
American Psychological Association (APA)
Fujimaki, Shin& Wakabayashi, Tamami& Takemasa, Tohru& Asashima, Makoto& Warashina, Masaki. 2015. Diabetes and Stem Cell Function. BioMed Research International،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1056044
Modern Language Association (MLA)
Fujimaki, Shin…[et al.]. Diabetes and Stem Cell Function. BioMed Research International No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1056044
American Medical Association (AMA)
Fujimaki, Shin& Wakabayashi, Tamami& Takemasa, Tohru& Asashima, Makoto& Warashina, Masaki. Diabetes and Stem Cell Function. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1056044
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056044