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An Update on Renal Artery Denervation and Its Clinical Impact on Hypertensive Disease
Joint Authors
Kuang, Ye Min
Gan, Gary C. H.
Burgess, David
Denniss, Alan Robert
Bhat, Aditya
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Hypertension is a globally prevalent condition, with a heavy clinical and economic burden.
It is the predominant risk factor for premature cardiovascular and cerebrovascular disease, and is associated with a variety of clinical disorders including stroke, congestive cardiac failure, ischaemic heart disease, chronic renal failure, and peripheral arterial disease.
A significant subset of hypertensive patients have resistant hypertensive disease.
In this group of patients, catheter-based renal artery denervation has emerged as a potential therapy, with favourable clinical efficacy and safety in early trials.
Additional benefits of this therapy are also being identified and include effects on left ventricular remodeling, cardiac performance, and symptom status in congestive cardiac failure.
Utility of renal denervation for the management of resistant hypertension, however, has become controversial since the release of the Symplicity HTN-3 trial, the first large-scale blinded randomised study investigating the efficacy and safety of renal artery denervation.
The aim of this paper is to evaluate the history, utility, and clinical efficacy of renal artery denervation technology, including an in-depth appraisal of the current literature and principal trials.
American Psychological Association (APA)
Bhat, Aditya& Kuang, Ye Min& Gan, Gary C. H.& Burgess, David& Denniss, Alan Robert. 2015. An Update on Renal Artery Denervation and Its Clinical Impact on Hypertensive Disease. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1056103
Modern Language Association (MLA)
Bhat, Aditya…[et al.]. An Update on Renal Artery Denervation and Its Clinical Impact on Hypertensive Disease. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1056103
American Medical Association (AMA)
Bhat, Aditya& Kuang, Ye Min& Gan, Gary C. H.& Burgess, David& Denniss, Alan Robert. An Update on Renal Artery Denervation and Its Clinical Impact on Hypertensive Disease. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1056103
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056103