Evaluation of Toxic, Cytotoxic, Mutagenic, and Antimutagenic Activities of Natural and Technical Cashew Nut Shell Liquids Using the Allium cepa and Artemia salina Bioassays
Joint Authors
Oliveira, George L. S.
Leite, Aracelli de Sousa
Dantas, Alisson Ferreira
Gomes Júnior, Antonio L.
de Lima, Sidney Gonçalo
de Freitas, Rivelilson M.
Melo-Cavalcante, Ana Amélia de C.
Lopes Citó, Antonia Maria das Graças
Dantas Lopes, José Arimateia
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-10
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
The cashew nut releases a substance that is known as cashew nut shell liquid (CNSL).
There are both natural (iCNSL) and technical (tCNSL) cashew nut shell liquids.
This study used an Artemia salina bioassay to evaluate the toxic effects of iCNSL and tCNSL cashew nut shell liquids.
It also evaluated the toxicity, cytotoxicity, and mutagenicity of CNSL and its effects on the damage induced by copper sulfate (CuSO4·5H2O) on the meristems’ root of Allium cepa.
Effects of the damage induced by CuSO4·5H2O were evaluated before (pre-), during (co-), and after (post-) treatments.
The iCNSL contained 94.5% anacardic acid, and the tCNSL contained 91.3% cardanol.
The liquids were toxic to A.
salina.
Toxicity, cytotoxicity, and mutagenicity were observed with iCNSL compared with the negative control.
Similarly, iCNSL failed to inhibit the toxicity and cytotoxicity of CuSO4·5H2O.
The tCNSL was not toxic, cytotoxic, or mutagenic in any of the concentrations.
However, the lowest iCNSL concentrations and all of the tCNSL concentrations had preventive, antimutagenic, and reparative effects on micronuclei and on chromosomal aberrations in the A.
cepa.
Therefore, protective, modulating, and reparative effects may be observed in the A.
cepa, depending on the concentration and type of CNSL used.
American Psychological Association (APA)
Leite, Aracelli de Sousa& Dantas, Alisson Ferreira& Oliveira, George L. S.& Gomes Júnior, Antonio L.& de Lima, Sidney Gonçalo& Lopes Citó, Antonia Maria das Graças…[et al.]. 2015. Evaluation of Toxic, Cytotoxic, Mutagenic, and Antimutagenic Activities of Natural and Technical Cashew Nut Shell Liquids Using the Allium cepa and Artemia salina Bioassays. BioMed Research International،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1056185
Modern Language Association (MLA)
Leite, Aracelli de Sousa…[et al.]. Evaluation of Toxic, Cytotoxic, Mutagenic, and Antimutagenic Activities of Natural and Technical Cashew Nut Shell Liquids Using the Allium cepa and Artemia salina Bioassays. BioMed Research International No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1056185
American Medical Association (AMA)
Leite, Aracelli de Sousa& Dantas, Alisson Ferreira& Oliveira, George L. S.& Gomes Júnior, Antonio L.& de Lima, Sidney Gonçalo& Lopes Citó, Antonia Maria das Graças…[et al.]. Evaluation of Toxic, Cytotoxic, Mutagenic, and Antimutagenic Activities of Natural and Technical Cashew Nut Shell Liquids Using the Allium cepa and Artemia salina Bioassays. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1056185
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056185