The Role of Extracellular Vesicles: An Epigenetic View of the Cancer Microenvironment
Joint Authors
Qian, Zhongrun
Shen, Qi
Yang, Xi
Qiu, Yongming
Zhang, Wenbin
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Exosomes, microvesicles, and other extracellular vesicles are released by many cell types, including cancer cells and cancer-related immune cells.
Extracellular vesicles can directly or indirectly facilitate the transfer of bioinformation to recipient cells or to the extracellular environment.
In cancer, exosomes have been implicated in tumor initiation, proliferation, and metastasis.
Extracellular vesicles can transmit proteins and nucleic acids that participate in DNA methylation, histone modification, and posttranscriptional regulation of RNA.
Factors transmitted by extracellular vesicles reflect the donor cell status, and extracellular vesicles derived from tumor cells may be also responsible for altering expression of tumor promoting and tumor suppressing genes in recipient cells.
Thus, circulating extracellular vesicles may act as biomarkers of cancer, and detection of these biomarkers may be applied to diagnosis or assessment of prognosis in patients with cancer.
American Psychological Association (APA)
Qian, Zhongrun& Shen, Qi& Yang, Xi& Qiu, Yongming& Zhang, Wenbin. 2015. The Role of Extracellular Vesicles: An Epigenetic View of the Cancer Microenvironment. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056280
Modern Language Association (MLA)
Qian, Zhongrun…[et al.]. The Role of Extracellular Vesicles: An Epigenetic View of the Cancer Microenvironment. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1056280
American Medical Association (AMA)
Qian, Zhongrun& Shen, Qi& Yang, Xi& Qiu, Yongming& Zhang, Wenbin. The Role of Extracellular Vesicles: An Epigenetic View of the Cancer Microenvironment. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056280
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056280