A Novel Shape Memory Plate Osteosynthesis for Noninvasive Modulation of Fixation Stiffness in a Rabbit Tibia Osteotomy Model
Joint Authors
Hurschler, Ch.
Pfeifer, Ronny
Meier, Karen
Reifenrath, Janin
Gösling, Thomas
Wesling, Volker
Krämer, Manuel
Krettek, Christian
Decker, Sebastian
Müller, Christian W.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Nickel-titanium shape memory alloy (NiTi-SMA) implants might allow modulating fracture healing, changing their stiffness through alteration of both elastic modulus and cross-sectional shape by employing the shape memory effect (SME).
Hypotheses: a novel NiTi-SMA plate stabilizes tibia osteotomies in rabbits.
After noninvasive electromagnetic induction heating the alloy exhibits the SME and the plate changes towards higher stiffness (inverse dynamization) resulting in increased fixation stiffness and equal or better bony healing.
In 14 rabbits, 1.0 mm tibia osteotomies were fixed with our experimental plate.
Animals were randomised for control or induction heating at three weeks postoperatively.
Repetitive X-ray imaging and in vivo measurements of bending stiffness were performed.
After sacrifice at 8 weeks, macroscopic evaluation, µCT, and post mortem bending tests of the tibiae were carried out.
One death and one early implant dislocation occurred.
Following electromagnetic induction heating, radiographic and macroscopic changes of the implant proved successful SME activation.
All osteotomies healed.
In the treatment group, bending stiffness increased over time.
Differences between groups were not significant.
In conclusion, we demonstrated successful healing of rabbit tibia osteotomies using our novel NiTi-SMA plate.
We demonstrated shape-changing SME in-vivo through transcutaneous electromagnetic induction heating.
Thus, future orthopaedic implants could be modified without additional surgery.
American Psychological Association (APA)
Müller, Christian W.& Pfeifer, Ronny& Meier, Karen& Decker, Sebastian& Reifenrath, Janin& Gösling, Thomas…[et al.]. 2015. A Novel Shape Memory Plate Osteosynthesis for Noninvasive Modulation of Fixation Stiffness in a Rabbit Tibia Osteotomy Model. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056302
Modern Language Association (MLA)
Müller, Christian W.…[et al.]. A Novel Shape Memory Plate Osteosynthesis for Noninvasive Modulation of Fixation Stiffness in a Rabbit Tibia Osteotomy Model. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1056302
American Medical Association (AMA)
Müller, Christian W.& Pfeifer, Ronny& Meier, Karen& Decker, Sebastian& Reifenrath, Janin& Gösling, Thomas…[et al.]. A Novel Shape Memory Plate Osteosynthesis for Noninvasive Modulation of Fixation Stiffness in a Rabbit Tibia Osteotomy Model. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056302
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056302