Does High Thoracic Epidural Analgesia with Levobupivacaine Preserve Myocardium? A Prospective Randomized Study
Joint Authors
Bektas, Serife Gokbulut
Karadeniz, Umit
Ozturk, Burcin
Yavas, Soner
Biricik, Dilan
Saydam, Gul Sevim
Erdemli, Ozcan
Turan, Sema
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Our study aimed to compare HTEA and intravenous patient-controlled analgesia (PCA) in patients undergoing coronary bypass graft surgery (CABG), based on haemodynamic parameters and myocardial functions.
Materials and Methods.
The study included 34 patients that were scheduled for elective CABG, who were randomly divided into 2 groups.
Anesthesia was induced and maintained with total intravenous anesthesia in both groups while intravenous PCA with morphine was administered in Group 1 and infusion of levobupivacaine was administered from the beginning of the anesthesia in Group 2 by thoracic epidural catheter.
Blood samples were obtained presurgically, at 6 and 24 hours after surgery for troponin I, creatinine kinase-MB (CK-MB), total antioxidant capacity, and malondialdehyde.
Postoperative pain was evaluated every 4 hours until 24 hours via VAS.
Results.
There were significant differences in troponin I or CK-MB values between the groups at postsurgery 6 h and 24 h.
Heart rate and mean arterial pressure in Group 1 were significantly higher than in Group 2 at all measurements.
Cardiac index in Group 2 was significantly higher than in Group 1 at all measurements.
Conclusion.
Patients that underwent CABG and received HTEA had better myocardial function and perioperative haemodynamic parameters than those who did not receive HTEA.
American Psychological Association (APA)
Bektas, Serife Gokbulut& Turan, Sema& Karadeniz, Umit& Ozturk, Burcin& Yavas, Soner& Biricik, Dilan…[et al.]. 2015. Does High Thoracic Epidural Analgesia with Levobupivacaine Preserve Myocardium? A Prospective Randomized Study. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1056316
Modern Language Association (MLA)
Bektas, Serife Gokbulut…[et al.]. Does High Thoracic Epidural Analgesia with Levobupivacaine Preserve Myocardium? A Prospective Randomized Study. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1056316
American Medical Association (AMA)
Bektas, Serife Gokbulut& Turan, Sema& Karadeniz, Umit& Ozturk, Burcin& Yavas, Soner& Biricik, Dilan…[et al.]. Does High Thoracic Epidural Analgesia with Levobupivacaine Preserve Myocardium? A Prospective Randomized Study. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1056316
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056316