Actual Anatomical and Dosimetric Changes of Parotid Glands in Nasopharyngeal Carcinoma Patients during Intensity Modulated Radiation Therapy
Joint Authors
Feng, Lin-Chun
Ren, Gang
Du, Lei
Qu, Bao-Lin
Liu, Hai-Xia
Xie, Chuan-Bin
Xu, Shou-Ping
Ma, Lin
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The goal of this study was to evaluate the actual anatomical and dosimetric changes of parotid glands in nasopharyngeal carcinoma patients during intensity modulated radiation therapy.
With helical tomotherapy, its planning system, and adaptive software, weekly anatomical and dosimetric changes of parotid glands in 35 NPC patients were evaluated.
Interweekly parotid volume varied significantly ( P < 0.03 ).
The rate of volume change reached the highest level at the 16th fraction.
The average V 1 increased by 32.2 (left) and 28.6 (right), and the average D 50 increased by 33.9 (left) and 24.93 (right), respectively.
Repeat data comparison indicated that the V 1 and D 50 varied significantly among different fractions (both with P = 0.000 ).
The variation of parotid volume was inversely correlated with that of the V 1 and D 50 (both with P = 0.000 ).
In conclusion, parotid volume and actual dose vary significantly in NPC patients during IMRT.
Replanning at the end of the fourth week of IMRT may have clinical benefits.
American Psychological Association (APA)
Ren, Gang& Xu, Shou-Ping& Du, Lei& Feng, Lin-Chun& Qu, Bao-Lin& Liu, Hai-Xia…[et al.]. 2015. Actual Anatomical and Dosimetric Changes of Parotid Glands in Nasopharyngeal Carcinoma Patients during Intensity Modulated Radiation Therapy. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056324
Modern Language Association (MLA)
Ren, Gang…[et al.]. Actual Anatomical and Dosimetric Changes of Parotid Glands in Nasopharyngeal Carcinoma Patients during Intensity Modulated Radiation Therapy. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056324
American Medical Association (AMA)
Ren, Gang& Xu, Shou-Ping& Du, Lei& Feng, Lin-Chun& Qu, Bao-Lin& Liu, Hai-Xia…[et al.]. Actual Anatomical and Dosimetric Changes of Parotid Glands in Nasopharyngeal Carcinoma Patients during Intensity Modulated Radiation Therapy. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056324
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056324