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Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases
Joint Authors
Nie, Mao
Deng, Zhong-Liang
Liu, Jianming
Wang, Da-Zhi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-14
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
A healthy and independent life requires skeletal muscles to maintain optimal function throughout the lifespan, which is in turn dependent on efficient activation of processes that regulate muscle development, homeostasis, and metabolism.
Thus, identifying mechanisms that modulate these processes is of crucial priority.
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), have emerged as a class of previously unrecognized transcripts whose importance in a wide range of biological processes and human disease is only starting to be appreciated.
In this review, we summarize the roles of recently identified miRNAs and lncRNAs during skeletal muscle development and pathophysiology.
We also discuss several molecular mechanisms of these noncoding RNAs.
Undoubtedly, further systematic understanding of these noncoding RNAs’ functions and mechanisms will not only greatly expand our knowledge of basic skeletal muscle biology, but also significantly facilitate the development of therapies for various muscle diseases, such as muscular dystrophies, cachexia, and sarcopenia.
American Psychological Association (APA)
Nie, Mao& Deng, Zhong-Liang& Liu, Jianming& Wang, Da-Zhi. 2015. Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases. BioMed Research International،Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1056352
Modern Language Association (MLA)
Nie, Mao…[et al.]. Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases. BioMed Research International No. 2015 (2015), pp.1-17.
https://search.emarefa.net/detail/BIM-1056352
American Medical Association (AMA)
Nie, Mao& Deng, Zhong-Liang& Liu, Jianming& Wang, Da-Zhi. Noncoding RNAs, Emerging Regulators of Skeletal Muscle Development and Diseases. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1056352
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056352