Antibacterial Mechanisms of Polymyxin and Bacterial Resistance
Joint Authors
Yu, Zhiliang
Qiu, Juanping
Qin, Wangrong
Lin, Jianxun
Fang, Shisong
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-15
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Multidrug resistance in pathogens is an increasingly significant threat for human health.
Indeed, some strains are resistant to almost all currently available antibiotics, leaving very limited choices for antimicrobial clinical therapy.
In many such cases, polymyxins are the last option available, although their use increases the risk of developing resistant strains.
This review mainly aims to discuss advances in unraveling the mechanisms of antibacterial activity of polymyxins and bacterial tolerance together with the description of polymyxin structure, synthesis, and structural modification.
These are expected to help researchers not only develop a series of new polymyxin derivatives necessary for future medical care, but also optimize the clinical use of polymyxins with minimal resistance development.
American Psychological Association (APA)
Yu, Zhiliang& Qin, Wangrong& Lin, Jianxun& Fang, Shisong& Qiu, Juanping. 2015. Antibacterial Mechanisms of Polymyxin and Bacterial Resistance. BioMed Research International،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1056359
Modern Language Association (MLA)
Yu, Zhiliang…[et al.]. Antibacterial Mechanisms of Polymyxin and Bacterial Resistance. BioMed Research International No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1056359
American Medical Association (AMA)
Yu, Zhiliang& Qin, Wangrong& Lin, Jianxun& Fang, Shisong& Qiu, Juanping. Antibacterial Mechanisms of Polymyxin and Bacterial Resistance. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1056359
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056359