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MicroRNAs and Cardiovascular Diseases
Joint Authors
Imanishi, Toshio
Nishiguchi, Tsuyoshi
Akasaka, Takashi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-01
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Coronary artery diseases (CAD) and heart failure have high mortality rate in the world, although much progress has been made in this field in last two decades.
There is still a clinical need for a novel diagnostic approach and a therapeutic strategy to decrease the incidence of CAD.
MicroRNAs (miRNAs) are highly conserved noncoding small RNA molecules that regulate a large fraction of the genome by binding to complementary messenger RNA sequences, resulting in posttranscriptional gene silencing.
Recent studies have shown that specific miRNAs are involved in whole stage of atherosclerosis, from endothelium dysfunction to plaque rupture.
These findings suggest that miRNAs are potential biomarkers in early diagnosis and therapeutic targets in CAD.
In the present review, we highlight the role of miRNAs in every stage of atherosclerosis, and discuss the prospects of miRNAs in the near future.
American Psychological Association (APA)
Nishiguchi, Tsuyoshi& Imanishi, Toshio& Akasaka, Takashi. 2015. MicroRNAs and Cardiovascular Diseases. BioMed Research International،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1056372
Modern Language Association (MLA)
Nishiguchi, Tsuyoshi…[et al.]. MicroRNAs and Cardiovascular Diseases. BioMed Research International No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1056372
American Medical Association (AMA)
Nishiguchi, Tsuyoshi& Imanishi, Toshio& Akasaka, Takashi. MicroRNAs and Cardiovascular Diseases. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1056372
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056372