Reproducibility of Neonate Ocular Circulation Measurements Using Laser Speckle Flowgraphy
Joint Authors
Matsumoto, Tadashi
Itokawa, Takashi
Shiba, Tomoaki
Katayama, Yuji
Arimura, Tetsushi
Mizukaki, Norio
Yoda, Hitoshi
Hori, Yuichi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Measuring the ocular blood flow in neonates may clarify the relationships between eye diseases and ocular circulation abnormalities.
However, no method for noninvasively measuring ocular circulation in neonates is established.
We used laser speckle flowgraphy (LSFG) modified for neonates to measure their ocular circulation and investigated whether this method is reproducible.
During their normal sleep, we studied 16 subjects (adjusted age of 34–48 weeks) whose blood flow could be measured three consecutive times.
While the subjects slept in the supine position, three mean blur rate (MBR) values of the optic nerve head (ONH) were obtained: the MBR-A (mean of all values), MBR-V (vessel mean), and MBR-T (tissue mean), and nine blood flow pulse waveform parameters in the ONH were examined.
We analyzed the coefficient of variation (COV) and the intraclass correlation coefficient (ICC) for each parameter.
The COVs of the MBR values were all ≤10%.
The ICCs of the MBR values were all >0.8.
Good COVs were observed for the blowout score, blowout time, rising rate, falling rate, and acceleration time index.
Although the measurement of ocular circulation in the neonates was difficult, our results exhibited reproducibility, suggesting that this method could be used in clinical research.
American Psychological Association (APA)
Matsumoto, Tadashi& Itokawa, Takashi& Shiba, Tomoaki& Katayama, Yuji& Arimura, Tetsushi& Mizukaki, Norio…[et al.]. 2015. Reproducibility of Neonate Ocular Circulation Measurements Using Laser Speckle Flowgraphy. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056408
Modern Language Association (MLA)
Matsumoto, Tadashi…[et al.]. Reproducibility of Neonate Ocular Circulation Measurements Using Laser Speckle Flowgraphy. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056408
American Medical Association (AMA)
Matsumoto, Tadashi& Itokawa, Takashi& Shiba, Tomoaki& Katayama, Yuji& Arimura, Tetsushi& Mizukaki, Norio…[et al.]. Reproducibility of Neonate Ocular Circulation Measurements Using Laser Speckle Flowgraphy. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056408
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056408