Magnetic Resonance Image Sequence Influences the Relationship between Bone Marrow Lesions Volume and Pain: Data from the Osteoarthritis Initiative
Joint Authors
Driban, Jeffrey B.
Zhang, Ming
Price, Lori Lyn
Lo, Grace H.
McAlindon, Timothy E.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-02
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Subchondral bone marrow lesions (BMLs) are related to structural and symptomatic osteoarthritis progression.
However, it is unclear how sequence selection influences a quantitative BML measurement and its construct validity.
We compared quantitative assessment of BMLs on intermediate-weighted fat suppressed (IW FS) turbo spin echo and 3-dimensional dual echo steady state (3D DESS) sequences.
We used a customized software to measure 30 knees’ (24- and 48-month MR images) BMLs on both sequences.
The results showed that the IW FS sequences have much larger BML volumes (median: IW FS = 1840 mm3; DESS = 191 mm3) and BML volume change (between 24 and 48 months) than DESS sequence and demonstrate more BML volume change.
The 24-month BML volume on IW FS is correlated with BML volume on DESS (rs = 0.83).
BML volume change on IW FS is not significantly correlated with change on DESS.
The 24-month WOMAC pain is correlated with the 24-month BMLs on IW FS (rs = 0.39) but not DESS.
The change in WOMAC pain is correlated with BML volume change on IW FS (rs = 0.37) but not DESS.
Overall, BML quantification on IW FS offers better validity and statistical power than BML quantification on a 3D DESS sequence.
American Psychological Association (APA)
Zhang, Ming& Driban, Jeffrey B.& Price, Lori Lyn& Lo, Grace H.& McAlindon, Timothy E.. 2015. Magnetic Resonance Image Sequence Influences the Relationship between Bone Marrow Lesions Volume and Pain: Data from the Osteoarthritis Initiative. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1056551
Modern Language Association (MLA)
Zhang, Ming…[et al.]. Magnetic Resonance Image Sequence Influences the Relationship between Bone Marrow Lesions Volume and Pain: Data from the Osteoarthritis Initiative. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1056551
American Medical Association (AMA)
Zhang, Ming& Driban, Jeffrey B.& Price, Lori Lyn& Lo, Grace H.& McAlindon, Timothy E.. Magnetic Resonance Image Sequence Influences the Relationship between Bone Marrow Lesions Volume and Pain: Data from the Osteoarthritis Initiative. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1056551
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056551